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SMILES: COc1cc(cc(OC)c1OC)-c1cnc2[nH]cc(-c3ccc4n(C)ccc4c3)c2c1
InChI Key: InChIKey=IDDMQFIMAPLOGU-UHFFFAOYSA-N
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human)) | BDBM354747 (Preparation of 3-(1-methyl-1H-indol-5-yl)-5-(3,4,5...) | PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet  | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Rochester; Board of Regents of the University of Nebraska US Patent | Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ... | US Patent US10485800 (2019) BindingDB Entry DOI: 10.7270/Q22B91DW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human)) | BDBM354747 (Preparation of 3-(1-methyl-1H-indol-5-yl)-5-(3,4,5...) | PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Rochester US Patent | Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ... | US Patent US9814704 (2017) BindingDB Entry DOI: 10.7270/Q27H1MRN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
