null

SMILES: COc1cc(cc(OC)c1OC)-c1cnc2[nH]cc(-c3ccc(cc3)C(N)=O)c2c1

InChI Key: InChIKey=KFPRSPRIHQMUJC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 354748   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354748 (Preparation of 4-(5-(3,4,5-trimethoxyphenyl)-1H-py...) Show SMILES COc1cc(cc(OC)c1OC)-c1cnc2[nH]cc(-c3ccc(cc3)C(N)=O)c2c1 Show InChI InChI=1S/C23H21N3O4/c1-28-19-9-15(10-20(29-2)21(19)30-3)16-8-17-18(12-26-23(17)25-11-16)13-4-6-14(7-5-13)22(24)27/h4-12H,1-3H3,(H2,24,27)(H,25,26)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester; Board of Regents of the University of Nebraska US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US10485800 (2019) BindingDB Entry DOI: 10.7270/Q22B91DW
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354748 (Preparation of 4-(5-(3,4,5-trimethoxyphenyl)-1H-py...) Show SMILES COc1cc(cc(OC)c1OC)-c1cnc2[nH]cc(-c3ccc(cc3)C(N)=O)c2c1 Show InChI InChI=1S/C23H21N3O4/c1-28-19-9-15(10-20(29-2)21(19)30-3)16-8-17-18(12-26-23(17)25-11-16)13-4-6-14(7-5-13)22(24)27/h4-12H,1-3H3,(H2,24,27)(H,25,26)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US9814704 (2017) BindingDB Entry DOI: 10.7270/Q27H1MRN
					More data for this Ligand-Target Pair