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SMILES: Cc1ccc(cc1)S(=O)(=O)n1cc(-c2ccc3[nH]ccc3c2)c2cc(cnc12)-c1ccc(C=O)cc1

InChI Key: InChIKey=ANQUZKPKKVNPTD-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 354755   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase kinase kinase 11


(Homo sapiens (Human))		BDBM354755
PNG
(US9814704, Example 32)
Show SMILES Cc1ccc(cc1)S(=O)(=O)n1cc(-c2ccc3[nH]ccc3c2)c2cc(cnc12)-c1ccc(C=O)cc1
Show InChI InChI=1S/C29H21N3O3S/c1-19-2-9-25(10-3-19)36(34,35)32-17-27(22-8-11-28-23(14-22)12-13-30-28)26-15-24(16-31-29(26)32)21-6-4-20(18-33)5-7-21/h2-18,30H,1H3
PDB

NCI pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



The University of Rochester

US Patent


Assay Description
200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...

US Patent US9814704 (2017)


BindingDB Entry DOI: 10.7270/Q27H1MRN
More data for this
Ligand-Target Pair