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SMILES: CNC(=O)c1ccc(cc1)-c1c[nH]c2ncc(cc12)-c1ccc(CN2CCN(C)CC2)cc1

InChI Key: InChIKey=KUCQMLFHLSDMKS-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 354888   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354888 (Preparation of N-methyl-4-{5-[4-(4-methyl-piperazi...) Show SMILES CNC(=O)c1ccc(cc1)-c1c[nH]c2ncc(cc12)-c1ccc(CN2CCN(C)CC2)cc1 Show InChI InChI=1S/C27H29N5O/c1-28-27(33)22-9-7-21(8-10-22)25-17-30-26-24(25)15-23(16-29-26)20-5-3-19(4-6-20)18-32-13-11-31(2)12-14-32/h3-10,15-17H,11-14,18H2,1-2H3,(H,28,33)(H,29,30)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester; Board of Regents of the University of Nebraska US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US10485800 (2019) BindingDB Entry DOI: 10.7270/Q22B91DW
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354888 (Preparation of N-methyl-4-{5-[4-(4-methyl-piperazi...) Show SMILES CNC(=O)c1ccc(cc1)-c1c[nH]c2ncc(cc12)-c1ccc(CN2CCN(C)CC2)cc1 Show InChI InChI=1S/C27H29N5O/c1-28-27(33)22-9-7-21(8-10-22)25-17-30-26-24(25)15-23(16-29-26)20-5-3-19(4-6-20)18-32-13-11-31(2)12-14-32/h3-10,15-17H,11-14,18H2,1-2H3,(H,28,33)(H,29,30)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US9814704 (2017) BindingDB Entry DOI: 10.7270/Q27H1MRN
					More data for this Ligand-Target Pair