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SMILES: CCOc1ccn(-c2ccc(F)cc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnn3ccc(-c4cccc(N)c4)c23)c(F)c1

InChI Key: InChIKey=QRQWUJWPSKSZIJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 355861   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM355861
PNG
(4-ethoxy-N-(3-fluoro-4-((5-(3-aminophenyl)pyrrolo[...)
Show SMILES CCOc1ccn(-c2ccc(F)cc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnn3ccc(-c4cccc(N)c4)c23)c(F)c1
Show InChI InChI=1S/C33H25F2N5O4/c1-2-43-28-14-16-39(24-9-6-21(34)7-10-24)33(42)30(28)32(41)38-23-8-11-27(26(35)19-23)44-29-12-15-37-40-17-13-25(31(29)40)20-4-3-5-22(36)18-20/h3-19H,2,36H2,1H3,(H,38,41)
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US Patent
n/an/a<40n/an/an/an/an/an/a



The Asan Foundation

US Patent


Assay Description
The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...

US Patent US9815840 (2017)


BindingDB Entry DOI: 10.7270/Q2862JQZ
More data for this
Ligand-Target Pair