null
SMILES: CN(C)Cc1ccc(Cl)c(c1)-c1ccn2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)c12
InChI Key: InChIKey=JOGAZZVDCRQKNW-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM355867 (N-(4-((5-(2-chloro-5-((dimethylamino)methyl)phenyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <40 | n/a | n/a | n/a | n/a | n/a | n/a |
The Asan Foundation US Patent | Assay Description The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept... | US Patent US9815840 (2017) BindingDB Entry DOI: 10.7270/Q2862JQZ | |||||||||||
More data for this Ligand-Target Pair |