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SMILES: CN(C)Cc1ccc(Cl)c(c1)-c1ccn2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)c12

InChI Key: InChIKey=JOGAZZVDCRQKNW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 355867   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM355867
PNG
(N-(4-((5-(2-chloro-5-((dimethylamino)methyl)phenyl...)
Show SMILES CN(C)Cc1ccc(Cl)c(c1)-c1ccn2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)c12
Show InChI InChI=1S/C33H28ClF2N5O3/c1-40(2)19-20-3-9-26(34)25(17-20)24-12-16-41-30(24)29(11-15-37-41)44-28-10-8-23(18-27(28)36)39-32(43)33(13-14-33)31(42)38-22-6-4-21(35)5-7-22/h3-12,15-18H,13-14,19H2,1-2H3,(H,38,42)(H,39,43)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<40n/an/an/an/an/an/a



The Asan Foundation

US Patent


Assay Description
The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...


US Patent US9815840 (2017)


BindingDB Entry DOI: 10.7270/Q2862JQZ
More data for this
Ligand-Target Pair