null

SMILES: COCCO[C@@H](C)c1c(NC(=O)Nc2cnc(c(Cl)c2)-n2nccn2)cnc2cc(Cl)nn12

InChI Key: InChIKey=KLORCIORIFOYTH-NSHDSACASA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 355915   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 [329-824] (Homo sapiens (Human))	BDBM355915 ((S)-1-(5-chloro-6- (2H-1,2,3-triazol-2- yl)pyridin...) Show SMILES COCCO[C@@H](C)c1c(NC(=O)Nc2cnc(c(Cl)c2)-n2nccn2)cnc2cc(Cl)nn12 |r| Show InChI InChI=1S/C19H19Cl2N9O3/c1-11(33-6-5-32-2)17-14(10-22-16-8-15(21)28-29(16)17)27-19(31)26-12-7-13(20)18(23-9-12)30-24-3-4-25-30/h3-4,7-11H,5-6H2,1-2H3,(H2,26,27,31)/t11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.00300	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The assay employs a short peptide substrate labeled with the single fluorophore PT14 as a fluorescence lifetime probe sensitive to the cleavage state...				US Patent US10442808 (2019) BindingDB Entry DOI: 10.7270/Q2S75JQ3
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM355915 ((S)-1-(5-chloro-6- (2H-1,2,3-triazol-2- yl)pyridin...) Show SMILES COCCO[C@@H](C)c1c(NC(=O)Nc2cnc(c(Cl)c2)-n2nccn2)cnc2cc(Cl)nn12 |r| Show InChI InChI=1S/C19H19Cl2N9O3/c1-11(33-6-5-32-2)17-14(10-22-16-8-15(21)28-29(16)17)27-19(31)26-12-7-13(20)18(23-9-12)30-24-3-4-25-30/h3-4,7-11H,5-6H2,1-2H3,(H2,26,27,31)/t11-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.00300	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ...				US Patent US9815842 (2017) BindingDB Entry DOI: 10.7270/Q24F1T0N
					More data for this Ligand-Target Pair