BDBM355980 1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-yl)-3-(2- methyl-7-(2- methyltetrahydrofuran- 2-yl)pyrazolo[1,5- a]pyrimidin-6-yl)urea::US10442808, Example 104::US9815842, Example 104

SMILES: Cc1cc2ncc(NC(=O)Nc3cnc(c(Cl)c3)-n3nccn3)c(n2n1)C1(C)CCCO1

InChI Key: InChIKey=FZKJNYBIZJLFQC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 355980   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 [329-824] (Homo sapiens (Human))	BDBM355980 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) Show SMILES Cc1cc2ncc(NC(=O)Nc3cnc(c(Cl)c3)-n3nccn3)c(n2n1)C1(C)CCCO1 Show InChI InChI=1S/C20H20ClN9O2/c1-12-8-16-22-11-15(17(29(16)28-12)20(2)4-3-7-32-20)27-19(31)26-13-9-14(21)18(23-10-13)30-24-5-6-25-30/h5-6,8-11H,3-4,7H2,1-2H3,(H2,26,27,31)	PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.00200	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The assay employs a short peptide substrate labeled with the single fluorophore PT14 as a fluorescence lifetime probe sensitive to the cleavage state...				US Patent US10442808 (2019) BindingDB Entry DOI: 10.7270/Q2S75JQ3
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM355980 (1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...) Show SMILES Cc1cc2ncc(NC(=O)Nc3cnc(c(Cl)c3)-n3nccn3)c(n2n1)C1(C)CCCO1 Show InChI InChI=1S/C20H20ClN9O2/c1-12-8-16-22-11-15(17(29(16)28-12)20(2)4-3-7-32-20)27-19(31)26-13-9-14(21)18(23-10-13)30-24-5-6-25-30/h5-6,8-11H,3-4,7H2,1-2H3,(H2,26,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.00200	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ...				US Patent US9815842 (2017) BindingDB Entry DOI: 10.7270/Q24F1T0N
					More data for this Ligand-Target Pair