BDBM356625 US10214477, Example 11

SMILES: OC1CCC(CC1)N[C@H]1C[C@@H]1c1ccc(OCc2cccc(c2)C(F)(F)F)nc1

InChI Key: InChIKey=PUISIQVWPSIHGR-TUNPWDSISA-N

Data: 3 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 356625   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM356625 (US10214477, Example 11) Show SMILES OC1CCC(CC1)N[C@H]1C[C@@H]1c1ccc(OCc2cccc(c2)C(F)(F)F)nc1 |r,wU:10.12,wD:8.8,(9.54,5.39,;8.21,4.62,;8.21,3.08,;6.87,2.31,;5.54,3.08,;5.54,4.62,;6.87,5.39,;4.21,2.31,;2.87,3.08,;2.1,4.41,;1.33,3.08,;,2.31,;-1.33,3.08,;-2.67,2.31,;-2.67,.77,;-4,,;-5.33,.77,;-6.67,,;-8,.77,;-9.34,,;-9.34,-1.54,;-8,-2.37,;-6.67,-1.54,;-8,-3.91,;-8,-5.45,;-9.54,-3.91,;-6.46,-3.91,;-1.33,,;,.77,)| Show InChI InChI=1S/C22H25F3N2O2/c23-22(24,25)16-3-1-2-14(10-16)13-29-21-9-4-15(12-26-21)19-11-20(19)27-17-5-7-18(28)8-6-17/h1-4,9-10,12,17-20,27-28H,5-8,11,13H2/t17?,18?,19-,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oryzon Genomics S.A. US Patent					Assay Description Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...				US Patent US10214477 (2019) BindingDB Entry DOI: 10.7270/Q2ZS2ZTB
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM356625 (US10214477, Example 11) Show SMILES OC1CCC(CC1)N[C@H]1C[C@@H]1c1ccc(OCc2cccc(c2)C(F)(F)F)nc1 |r,wU:10.12,wD:8.8,(9.54,5.39,;8.21,4.62,;8.21,3.08,;6.87,2.31,;5.54,3.08,;5.54,4.62,;6.87,5.39,;4.21,2.31,;2.87,3.08,;2.1,4.41,;1.33,3.08,;,2.31,;-1.33,3.08,;-2.67,2.31,;-2.67,.77,;-4,,;-5.33,.77,;-6.67,,;-8,.77,;-9.34,,;-9.34,-1.54,;-8,-2.37,;-6.67,-1.54,;-8,-3.91,;-8,-5.45,;-9.54,-3.91,;-6.46,-3.91,;-1.33,,;,.77,)| Show InChI InChI=1S/C22H25F3N2O2/c23-22(24,25)16-3-1-2-14(10-16)13-29-21-9-4-15(12-26-21)19-11-20(19)27-17-5-7-18(28)8-6-17/h1-4,9-10,12,17-20,27-28H,5-8,11,13H2/t17?,18?,19-,20+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.05E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oryzon Genomics S.A. US Patent					Assay Description Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...				US Patent US10214477 (2019) BindingDB Entry DOI: 10.7270/Q2ZS2ZTB
					More data for this Ligand-Target Pair
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM356625 (US10214477, Example 11) Show SMILES OC1CCC(CC1)N[C@H]1C[C@@H]1c1ccc(OCc2cccc(c2)C(F)(F)F)nc1 |r,wU:10.12,wD:8.8,(9.54,5.39,;8.21,4.62,;8.21,3.08,;6.87,2.31,;5.54,3.08,;5.54,4.62,;6.87,5.39,;4.21,2.31,;2.87,3.08,;2.1,4.41,;1.33,3.08,;,2.31,;-1.33,3.08,;-2.67,2.31,;-2.67,.77,;-4,,;-5.33,.77,;-6.67,,;-8,.77,;-9.34,,;-9.34,-1.54,;-8,-2.37,;-6.67,-1.54,;-8,-3.91,;-8,-5.45,;-9.54,-3.91,;-6.46,-3.91,;-1.33,,;,.77,)| Show InChI InChI=1S/C22H25F3N2O2/c23-22(24,25)16-3-1-2-14(10-16)13-29-21-9-4-15(12-26-21)19-11-20(19)27-17-5-7-18(28)8-6-17/h1-4,9-10,12,17-20,27-28H,5-8,11,13H2/t17?,18?,19-,20+/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.05E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oryzon Genomics S.A. US Patent					Assay Description Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...				US Patent US10214477 (2019) BindingDB Entry DOI: 10.7270/Q2ZS2ZTB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM356625 (US10214477, Example 11) Show SMILES OC1CCC(CC1)N[C@H]1C[C@@H]1c1ccc(OCc2cccc(c2)C(F)(F)F)nc1 |r,wU:10.12,wD:8.8,(9.54,5.39,;8.21,4.62,;8.21,3.08,;6.87,2.31,;5.54,3.08,;5.54,4.62,;6.87,5.39,;4.21,2.31,;2.87,3.08,;2.1,4.41,;1.33,3.08,;,2.31,;-1.33,3.08,;-2.67,2.31,;-2.67,.77,;-4,,;-5.33,.77,;-6.67,,;-8,.77,;-9.34,,;-9.34,-1.54,;-8,-2.37,;-6.67,-1.54,;-8,-3.91,;-8,-5.45,;-9.54,-3.91,;-6.46,-3.91,;-1.33,,;,.77,)| Show InChI InChI=1S/C22H25F3N2O2/c23-22(24,25)16-3-1-2-14(10-16)13-29-21-9-4-15(12-26-21)19-11-20(19)27-17-5-7-18(28)8-6-17/h1-4,9-10,12,17-20,27-28H,5-8,11,13H2/t17?,18?,19-,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	131	n/a	n/a	n/a	n/a	n/a	n/a
Oryzon Genomics S.A. US Patent					Assay Description Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...				US Patent US10214477 (2019) BindingDB Entry DOI: 10.7270/Q2ZS2ZTB
					More data for this Ligand-Target Pair
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM356625 (US10214477, Example 11) Show SMILES OC1CCC(CC1)N[C@H]1C[C@@H]1c1ccc(OCc2cccc(c2)C(F)(F)F)nc1 |r,wU:10.12,wD:8.8,(9.54,5.39,;8.21,4.62,;8.21,3.08,;6.87,2.31,;5.54,3.08,;5.54,4.62,;6.87,5.39,;4.21,2.31,;2.87,3.08,;2.1,4.41,;1.33,3.08,;,2.31,;-1.33,3.08,;-2.67,2.31,;-2.67,.77,;-4,,;-5.33,.77,;-6.67,,;-8,.77,;-9.34,,;-9.34,-1.54,;-8,-2.37,;-6.67,-1.54,;-8,-3.91,;-8,-5.45,;-9.54,-3.91,;-6.46,-3.91,;-1.33,,;,.77,)| Show InChI InChI=1S/C22H25F3N2O2/c23-22(24,25)16-3-1-2-14(10-16)13-29-21-9-4-15(12-26-21)19-11-20(19)27-17-5-7-18(28)8-6-17/h1-4,9-10,12,17-20,27-28H,5-8,11,13H2/t17?,18?,19-,20+/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oryzon Genomics S.A. US Patent					Assay Description Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...				US Patent US10214477 (2019) BindingDB Entry DOI: 10.7270/Q2ZS2ZTB
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM356625 (US10214477, Example 11) Show SMILES OC1CCC(CC1)N[C@H]1C[C@@H]1c1ccc(OCc2cccc(c2)C(F)(F)F)nc1 |r,wU:10.12,wD:8.8,(9.54,5.39,;8.21,4.62,;8.21,3.08,;6.87,2.31,;5.54,3.08,;5.54,4.62,;6.87,5.39,;4.21,2.31,;2.87,3.08,;2.1,4.41,;1.33,3.08,;,2.31,;-1.33,3.08,;-2.67,2.31,;-2.67,.77,;-4,,;-5.33,.77,;-6.67,,;-8,.77,;-9.34,,;-9.34,-1.54,;-8,-2.37,;-6.67,-1.54,;-8,-3.91,;-8,-5.45,;-9.54,-3.91,;-6.46,-3.91,;-1.33,,;,.77,)| Show InChI InChI=1S/C22H25F3N2O2/c23-22(24,25)16-3-1-2-14(10-16)13-29-21-9-4-15(12-26-21)19-11-20(19)27-17-5-7-18(28)8-6-17/h1-4,9-10,12,17-20,27-28H,5-8,11,13H2/t17?,18?,19-,20+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oryzon Genomics S.A. US Patent					Assay Description Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...				US Patent US10214477 (2019) BindingDB Entry DOI: 10.7270/Q2ZS2ZTB
					More data for this Ligand-Target Pair