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SMILES: Cc1c(F)cccc1-n1ncc(C(=O)N2CCc3cc(Cl)ccc23)c1N

InChI Key: InChIKey=SBYWYJFOTFVRCK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 356999   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM356999 ((5-Amino-1-(3-fluoro-2-methylphenyl)-1H-pyrazol-4-...) Show SMILES Cc1c(F)cccc1-n1ncc(C(=O)N2CCc3cc(Cl)ccc23)c1N Show InChI InChI=1S/C19H16ClFN4O/c1-11-15(21)3-2-4-16(11)25-18(22)14(10-23-25)19(26)24-8-7-12-9-13(20)5-6-17(12)24/h2-6,9-10H,7-8,22H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Almirall, S.A. US Patent					Assay Description Cell LinesStable cell lines expressing the full-length protein of the voltage-gated sodium channels Nav1.7 or Nav1.5, with or without one beta-1, bet...				US Patent US10214509 (2019) BindingDB Entry DOI: 10.7270/Q2FQ9ZWJ
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM356999 ((5-Amino-1-(3-fluoro-2-methylphenyl)-1H-pyrazol-4-...) Show SMILES Cc1c(F)cccc1-n1ncc(C(=O)N2CCc3cc(Cl)ccc23)c1N Show InChI InChI=1S/C19H16ClFN4O/c1-11-15(21)3-2-4-16(11)25-18(22)14(10-23-25)19(26)24-8-7-12-9-13(20)5-6-17(12)24/h2-6,9-10H,7-8,22H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Almirall, S.A. US Patent					Assay Description Cell LinesStable cell lines expressing the full-length protein of the voltage-gated sodium channels Nav1.7 or Nav1.5, with or without one beta-1, bet...				US Patent US10214509 (2019) BindingDB Entry DOI: 10.7270/Q2FQ9ZWJ
					More data for this Ligand-Target Pair