BDBM357002 5-Amino-3-ethyl-1-(2-methoxyphenyl)-N-(5-(trifluoromethyl)pyridin-2-yl)-1H-pyrazole-4-carboxamide::US10214509, Example 114

SMILES: CCc1nn(c(N)c1C(=O)Nc1ccc(cn1)C(F)(F)F)-c1ccccc1OC

InChI Key: InChIKey=MNPBSJCEWUOKHL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 357002   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM357002 (5-Amino-3-ethyl-1-(2-methoxyphenyl)-N-(5-(trifluor...) Show SMILES CCc1nn(c(N)c1C(=O)Nc1ccc(cn1)C(F)(F)F)-c1ccccc1OC Show InChI InChI=1S/C19H18F3N5O2/c1-3-12-16(17(23)27(26-12)13-6-4-5-7-14(13)29-2)18(28)25-15-9-8-11(10-24-15)19(20,21)22/h4-10H,3,23H2,1-2H3,(H,24,25,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Almirall, S.A. US Patent					Assay Description Cell LinesStable cell lines expressing the full-length protein of the voltage-gated sodium channels Nav1.7 or Nav1.5, with or without one beta-1, bet...				US Patent US10214509 (2019) BindingDB Entry DOI: 10.7270/Q2FQ9ZWJ
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM357002 (5-Amino-3-ethyl-1-(2-methoxyphenyl)-N-(5-(trifluor...) Show SMILES CCc1nn(c(N)c1C(=O)Nc1ccc(cn1)C(F)(F)F)-c1ccccc1OC Show InChI InChI=1S/C19H18F3N5O2/c1-3-12-16(17(23)27(26-12)13-6-4-5-7-14(13)29-2)18(28)25-15-9-8-11(10-24-15)19(20,21)22/h4-10H,3,23H2,1-2H3,(H,24,25,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Almirall, S.A. US Patent					Assay Description Cell LinesStable cell lines expressing the full-length protein of the voltage-gated sodium channels Nav1.7 or Nav1.5, with or without one beta-1, bet...				US Patent US10214509 (2019) BindingDB Entry DOI: 10.7270/Q2FQ9ZWJ
					More data for this Ligand-Target Pair