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SMILES: CCc1nn(c(N)c1C(=O)Nc1ccc(cn1)C(F)(F)F)-c1cccc(F)c1C

InChI Key: InChIKey=UWLSZMSRUXKANW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 357006   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM357006 (5-Amino-3-ethyl-1-(3-fluoro-2-methylphenyl)-N-[5-t...) Show SMILES CCc1nn(c(N)c1C(=O)Nc1ccc(cn1)C(F)(F)F)-c1cccc(F)c1C Show InChI InChI=1S/C19H17F4N5O/c1-3-13-16(17(24)28(27-13)14-6-4-5-12(20)10(14)2)18(29)26-15-8-7-11(9-25-15)19(21,22)23/h4-9H,3,24H2,1-2H3,(H,25,26,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Almirall, S.A. US Patent					Assay Description Cell LinesStable cell lines expressing the full-length protein of the voltage-gated sodium channels Nav1.7 or Nav1.5, with or without one beta-1, bet...				US Patent US10214509 (2019) BindingDB Entry DOI: 10.7270/Q2FQ9ZWJ
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM357006 (5-Amino-3-ethyl-1-(3-fluoro-2-methylphenyl)-N-[5-t...) Show SMILES CCc1nn(c(N)c1C(=O)Nc1ccc(cn1)C(F)(F)F)-c1cccc(F)c1C Show InChI InChI=1S/C19H17F4N5O/c1-3-13-16(17(24)28(27-13)14-6-4-5-12(20)10(14)2)18(29)26-15-8-7-11(9-25-15)19(21,22)23/h4-9H,3,24H2,1-2H3,(H,25,26,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Almirall, S.A. US Patent					Assay Description Cell LinesStable cell lines expressing the full-length protein of the voltage-gated sodium channels Nav1.7 or Nav1.5, with or without one beta-1, bet...				US Patent US10214509 (2019) BindingDB Entry DOI: 10.7270/Q2FQ9ZWJ
					More data for this Ligand-Target Pair