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SMILES: Nc1c(cnn1-c1ccccc1O)C(=O)Nc1ccc(cn1)C(F)(F)F

InChI Key: InChIKey=DFDAGLOIAMTISP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 357010   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM357010 (5-Amino-1-(2-hydroxyphenyl)-N-(5-(trifluoromethyl)...) Show SMILES Nc1c(cnn1-c1ccccc1O)C(=O)Nc1ccc(cn1)C(F)(F)F Show InChI InChI=1S/C16H12F3N5O2/c17-16(18,19)9-5-6-13(21-7-9)23-15(26)10-8-22-24(14(10)20)11-3-1-2-4-12(11)25/h1-8,25H,20H2,(H,21,23,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Almirall, S.A. US Patent					Assay Description Cell LinesStable cell lines expressing the full-length protein of the voltage-gated sodium channels Nav1.7 or Nav1.5, with or without one beta-1, bet...				US Patent US10214509 (2019) BindingDB Entry DOI: 10.7270/Q2FQ9ZWJ
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM357010 (5-Amino-1-(2-hydroxyphenyl)-N-(5-(trifluoromethyl)...) Show SMILES Nc1c(cnn1-c1ccccc1O)C(=O)Nc1ccc(cn1)C(F)(F)F Show InChI InChI=1S/C16H12F3N5O2/c17-16(18,19)9-5-6-13(21-7-9)23-15(26)10-8-22-24(14(10)20)11-3-1-2-4-12(11)25/h1-8,25H,20H2,(H,21,23,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Almirall, S.A. US Patent					Assay Description Cell LinesStable cell lines expressing the full-length protein of the voltage-gated sodium channels Nav1.7 or Nav1.5, with or without one beta-1, bet...				US Patent US10214509 (2019) BindingDB Entry DOI: 10.7270/Q2FQ9ZWJ
					More data for this Ligand-Target Pair