BDBM357012 5-Amino-N-(4-chlorophenyl)-1-(2-methoxyphenyl)-1H-imidazole-4-carboxamide::US10214509, Example 254

SMILES: COc1ccccc1-n1cnc(C(=O)Nc2ccc(Cl)cc2)c1N

InChI Key: InChIKey=QRHWRVOGYSGMTL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 357012   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM357012 (5-Amino-N-(4-chlorophenyl)-1-(2-methoxyphenyl)-1H-...) Show SMILES COc1ccccc1-n1cnc(C(=O)Nc2ccc(Cl)cc2)c1N Show InChI InChI=1S/C17H15ClN4O2/c1-24-14-5-3-2-4-13(14)22-10-20-15(16(22)19)17(23)21-12-8-6-11(18)7-9-12/h2-10H,19H2,1H3,(H,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Almirall, S.A. US Patent					Assay Description Cell LinesStable cell lines expressing the full-length protein of the voltage-gated sodium channels Nav1.7 or Nav1.5, with or without one beta-1, bet...				US Patent US10214509 (2019) BindingDB Entry DOI: 10.7270/Q2FQ9ZWJ
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM357012 (5-Amino-N-(4-chlorophenyl)-1-(2-methoxyphenyl)-1H-...) Show SMILES COc1ccccc1-n1cnc(C(=O)Nc2ccc(Cl)cc2)c1N Show InChI InChI=1S/C17H15ClN4O2/c1-24-14-5-3-2-4-13(14)22-10-20-15(16(22)19)17(23)21-12-8-6-11(18)7-9-12/h2-10H,19H2,1H3,(H,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Almirall, S.A. US Patent					Assay Description Cell LinesStable cell lines expressing the full-length protein of the voltage-gated sodium channels Nav1.7 or Nav1.5, with or without one beta-1, bet...				US Patent US10214509 (2019) BindingDB Entry DOI: 10.7270/Q2FQ9ZWJ
					More data for this Ligand-Target Pair