BDBM35715 benzazepine derivative, 13a

SMILES: CNC1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccc(Cl)cc12

InChI Key: InChIKey=RGOBOPOBXHVHKO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35715   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM35715 (benzazepine derivative, 13a) Show SMILES CNC1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccc(Cl)cc12 Show InChI InChI=1S/C26H26ClN3O2/c1-17-6-3-4-7-21(17)25(31)29-20-12-9-18(10-13-20)26(32)30-15-5-8-23(28-2)22-16-19(27)11-14-24(22)30/h3-4,6-7,9-14,16,23,28H,5,8,15H2,1-2H3,(H,29,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	7.4	4
Otsuka Pharmaceutical Co., Ltd					Assay Description After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...				Bioorg Med Chem 7: 1743-54 (1999) Article DOI: 10.1016/s0968-0896(99)00101-7 BindingDB Entry DOI: 10.7270/Q2W957JR
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM35715 (benzazepine derivative, 13a) Show SMILES CNC1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccc(Cl)cc12 Show InChI InChI=1S/C26H26ClN3O2/c1-17-6-3-4-7-21(17)25(31)29-20-12-9-18(10-13-20)26(32)30-15-5-8-23(28-2)22-16-19(27)11-14-24(22)30/h3-4,6-7,9-14,16,23,28H,5,8,15H2,1-2H3,(H,29,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	7.4	4
Otsuka Pharmaceutical Co., Ltd					Assay Description After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...				Bioorg Med Chem 7: 1743-54 (1999) Article DOI: 10.1016/s0968-0896(99)00101-7 BindingDB Entry DOI: 10.7270/Q2W957JR
					More data for this Ligand-Target Pair