BDBM35716 benzazepine derivative, 18

SMILES: Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCCC(NCC=C)c2cc(Cl)ccc12

InChI Key: InChIKey=VCWFFSIHQLCFHS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35716   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM35716 (benzazepine derivative, 18) Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCCC(NCC=C)c2cc(Cl)ccc12 Show InChI InChI=1S/C28H28ClN3O2/c1-3-16-30-25-9-6-17-32(26-15-12-21(29)18-24(25)26)28(34)20-10-13-22(14-11-20)31-27(33)23-8-5-4-7-19(23)2/h3-5,7-8,10-15,18,25,30H,1,6,9,16-17H2,2H3,(H,31,33)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	7.4	4
Otsuka Pharmaceutical Co., Ltd					Assay Description After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...				Bioorg Med Chem 7: 1743-54 (1999) Article DOI: 10.1016/s0968-0896(99)00101-7 BindingDB Entry DOI: 10.7270/Q2W957JR
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM35716 (benzazepine derivative, 18) Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCCC(NCC=C)c2cc(Cl)ccc12 Show InChI InChI=1S/C28H28ClN3O2/c1-3-16-30-25-9-6-17-32(26-15-12-21(29)18-24(25)26)28(34)20-10-13-22(14-11-20)31-27(33)23-8-5-4-7-19(23)2/h3-5,7-8,10-15,18,25,30H,1,6,9,16-17H2,2H3,(H,31,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	7.4	4
Otsuka Pharmaceutical Co., Ltd					Assay Description After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...				Bioorg Med Chem 7: 1743-54 (1999) Article DOI: 10.1016/s0968-0896(99)00101-7 BindingDB Entry DOI: 10.7270/Q2W957JR
					More data for this Ligand-Target Pair