BDBM35721 benzazepine derivative, 30

SMILES: Cc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCC(O)c3cc(Cl)ccc23)c(Cl)c1

InChI Key: InChIKey=DMDIUVQYZJYLSL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35721   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM35721 (benzazepine derivative, 30) Show SMILES Cc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCC(O)c3cc(Cl)ccc23)c(Cl)c1 Show InChI InChI=1S/C25H22Cl2N2O3/c1-15-5-2-3-6-18(15)24(31)28-17-9-10-19(21(27)14-17)25(32)29-12-4-7-23(30)20-13-16(26)8-11-22(20)29/h2-3,5-6,8-11,13-14,23,30H,4,7,12H2,1H3,(H,28,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	7.4	4
Otsuka Pharmaceutical Co., Ltd					Assay Description After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...				Bioorg Med Chem 7: 1743-54 (1999) Article DOI: 10.1016/s0968-0896(99)00101-7 BindingDB Entry DOI: 10.7270/Q2W957JR
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM35721 (benzazepine derivative, 30) Show SMILES Cc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCC(O)c3cc(Cl)ccc23)c(Cl)c1 Show InChI InChI=1S/C25H22Cl2N2O3/c1-15-5-2-3-6-18(15)24(31)28-17-9-10-19(21(27)14-17)25(32)29-12-4-7-23(30)20-13-16(26)8-11-22(20)29/h2-3,5-6,8-11,13-14,23,30H,4,7,12H2,1H3,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	7.4	4
Otsuka Pharmaceutical Co., Ltd					Assay Description After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...				Bioorg Med Chem 7: 1743-54 (1999) Article DOI: 10.1016/s0968-0896(99)00101-7 BindingDB Entry DOI: 10.7270/Q2W957JR
					More data for this Ligand-Target Pair