null
SMILES: COC(=O)c1nc2cc(ccc2[nH]1)-n1ncc(C(=O)c2cc3ccccc3[nH]2)c1N
InChI Key: InChIKey=PGRWVLHMKFTXIP-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM357247 (Methyl 5-(5-amino-4-(1H-indole-2-carbonyl)-1H-pyra...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 75.3 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent | Assay Description The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom... | US Patent US10214515 (2019) BindingDB Entry DOI: 10.7270/Q22J6F46 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 4 (Homo sapiens (Human)) | BDBM357247 (Methyl 5-(5-amino-4-(1H-indole-2-carbonyl)-1H-pyra...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent | Assay Description The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom... | US Patent US10214515 (2019) BindingDB Entry DOI: 10.7270/Q22J6F46 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 3 (Homo sapiens (Human)) | BDBM357247 (Methyl 5-(5-amino-4-(1H-indole-2-carbonyl)-1H-pyra...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >100 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent | Assay Description The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom... | US Patent US10214515 (2019) BindingDB Entry DOI: 10.7270/Q22J6F46 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 2 (Homo sapiens (Human)) | BDBM357247 (Methyl 5-(5-amino-4-(1H-indole-2-carbonyl)-1H-pyra...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent | Assay Description The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom... | US Patent US10214515 (2019) BindingDB Entry DOI: 10.7270/Q22J6F46 | |||||||||||
More data for this Ligand-Target Pair |