null

SMILES: Nc1c(cnn1-c1ccc2[nH]c(nc2c1)C1CC1)C(=O)c1cc2ccc(F)cc2[nH]1

InChI Key: InChIKey=HIDXCLAHVYKPCQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 357250   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM357250 ((5-Amino-1-(2-cyclopropyl-1H-benzo[d]imidazol-5-yl...) Show SMILES Nc1c(cnn1-c1ccc2[nH]c(nc2c1)C1CC1)C(=O)c1cc2ccc(F)cc2[nH]1 Show InChI InChI=1S/C22H17FN6O/c23-13-4-3-12-7-19(26-17(12)8-13)20(30)15-10-25-29(21(15)24)14-5-6-16-18(9-14)28-22(27-16)11-1-2-11/h3-11,26H,1-2,24H2,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...				US Patent US10214515 (2019) BindingDB Entry DOI: 10.7270/Q22J6F46
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM357250 ((5-Amino-1-(2-cyclopropyl-1H-benzo[d]imidazol-5-yl...) Show SMILES Nc1c(cnn1-c1ccc2[nH]c(nc2c1)C1CC1)C(=O)c1cc2ccc(F)cc2[nH]1 Show InChI InChI=1S/C22H17FN6O/c23-13-4-3-12-7-19(26-17(12)8-13)20(30)15-10-25-29(21(15)24)14-5-6-16-18(9-14)28-22(27-16)11-1-2-11/h3-11,26H,1-2,24H2,(H,27,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	308	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...				US Patent US10214515 (2019) BindingDB Entry DOI: 10.7270/Q22J6F46
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM357250 ((5-Amino-1-(2-cyclopropyl-1H-benzo[d]imidazol-5-yl...) Show SMILES Nc1c(cnn1-c1ccc2[nH]c(nc2c1)C1CC1)C(=O)c1cc2ccc(F)cc2[nH]1 Show InChI InChI=1S/C22H17FN6O/c23-13-4-3-12-7-19(26-17(12)8-13)20(30)15-10-25-29(21(15)24)14-5-6-16-18(9-14)28-22(27-16)11-1-2-11/h3-11,26H,1-2,24H2,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...				US Patent US10214515 (2019) BindingDB Entry DOI: 10.7270/Q22J6F46
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM357250 ((5-Amino-1-(2-cyclopropyl-1H-benzo[d]imidazol-5-yl...) Show SMILES Nc1c(cnn1-c1ccc2[nH]c(nc2c1)C1CC1)C(=O)c1cc2ccc(F)cc2[nH]1 Show InChI InChI=1S/C22H17FN6O/c23-13-4-3-12-7-19(26-17(12)8-13)20(30)15-10-25-29(21(15)24)14-5-6-16-18(9-14)28-22(27-16)11-1-2-11/h3-11,26H,1-2,24H2,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang Hisun Pharmaceutical Co., Ltd. US Patent					Assay Description The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...				US Patent US10214515 (2019) BindingDB Entry DOI: 10.7270/Q22J6F46
					More data for this Ligand-Target Pair