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BDBM357253 (5-Amino-1-(2-cyclopropyl-1H-benzo[d]imidazol-5-yl)-1H-pyrazol-4-yl)(6-(1-ethyl-1H-pyrazol-4-yl)-1H-indol-2-yl)methanone::US10214515, Example 16

SMILES:

InChI Key:

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 357253   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
VEGF-receptor 2 and Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM357253
PNG
((5-Amino-1-(2-cyclopropyl-1H-benzo[d]imidazol-5-yl...)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
US Patent
n/an/a 4.90n/an/an/an/an/an/a



University of Massachusetts Medical School





J Med Chem 50: 4316-28 (2007)


Article DOI: 10.1021/jm070284z
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor


(Homo sapiens (Human))
BDBM357253
PNG
((5-Amino-1-(2-cyclopropyl-1H-benzo[d]imidazol-5-yl...)
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
US Patent
n/an/a 280n/an/an/an/an/an/a



University of Massachusetts Medical School





J Med Chem 50: 4316-28 (2007)


Article DOI: 10.1021/jm070284z
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor


(Homo sapiens (Human))
BDBM357253
PNG
((5-Amino-1-(2-cyclopropyl-1H-benzo[d]imidazol-5-yl...)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
US Patent
n/an/a 6.80n/an/an/an/an/an/a



University of Massachusetts Medical School





J Med Chem 50: 4316-28 (2007)


Article DOI: 10.1021/jm070284z
More data for this
Ligand-Target Pair
VEGF-receptor 2 and Fibroblast growth factor receptor 2


(Homo sapiens (Human))
BDBM357253
PNG
((5-Amino-1-(2-cyclopropyl-1H-benzo[d]imidazol-5-yl...)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
US Patent
n/an/a 0.700n/an/an/an/an/an/a



University of Massachusetts Medical School





J Med Chem 50: 4316-28 (2007)


Article DOI: 10.1021/jm070284z
More data for this
Ligand-Target Pair