BindingDB PrimarySearch

null

SMILES: CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O

InChI Key: InChIKey=XEYBRNLFEZDVAW-ARSRFYASSA-N

PDB links: 9 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 83 hits for monomerid = 35847
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	0.110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cayman Chemical Company, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human recombinant EP4 receptor expressed in HEK293 cell membranes after 120 mins by liquid scintillation counting metho...				J Med Chem 62: 4731-4741 (2019) Article DOI: 10.1021/acs.jmedchem.9b00336 BindingDB Entry DOI: 10.7270/Q22R3W32
Cayman Chemical Company, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	0.330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by PDSP K_i Database									Biochim Biophys Acta 1483: 285-93 (2000) Article DOI: 10.1016/s1388-1981(99)00164-x BindingDB Entry DOI: 10.7270/Q2J964XQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	0.330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
EMD Serono Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 4323-7 (2007) Article DOI: 10.1016/j.bmcl.2007.05.025 BindingDB Entry DOI: 10.7270/Q2RF5VVC
EMD Serono Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	0.330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
EMD-Serono Research Institute, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 18: 821-4 (2008) Article DOI: 10.1016/j.bmcl.2007.11.020 BindingDB Entry DOI: 10.7270/Q2W096SW
EMD-Serono Research Institute, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	0.790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
EMD Serono Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 4323-7 (2007) Article DOI: 10.1016/j.bmcl.2007.05.025 BindingDB Entry DOI: 10.7270/Q2RF5VVC
EMD Serono Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	0.790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
EMD-Serono Research Institute Curated by ChEMBL					Assay Description Binding affinity at human prostaglandin EP4 receptor				Bioorg Med Chem Lett 17: 6572-5 (2007) Article DOI: 10.1016/j.bmcl.2007.09.074 BindingDB Entry DOI: 10.7270/Q29887V9
EMD-Serono Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	0.790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by PDSP K_i Database									Biochim Biophys Acta 1483: 285-93 (2000) Article DOI: 10.1016/s1388-1981(99)00164-x BindingDB Entry DOI: 10.7270/Q2J964XQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	0.790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
EMD-Serono Research Institute, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGE4 from human EP4 receptor				Bioorg Med Chem Lett 18: 821-4 (2008) Article DOI: 10.1016/j.bmcl.2007.11.020 BindingDB Entry DOI: 10.7270/Q2W096SW
EMD-Serono Research Institute, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	0.850	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by PDSP K_i Database									Br J Pharmacol 122: 217-24 (1997) Article DOI: 10.1038/sj.bjp.0701367 BindingDB Entry DOI: 10.7270/Q26M35CT
Kyoto University Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cayman Chemical Company, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human recombinant EP2 receptor expressed in HEK293 cell membranes after 120 mins by liquid scintillation counting metho...				J Med Chem 62: 4731-4741 (2019) Article DOI: 10.1021/acs.jmedchem.9b00336 BindingDB Entry DOI: 10.7270/Q22R3W32
Cayman Chemical Company, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by PDSP K_i Database									Br J Pharmacol 122: 217-24 (1997) Article DOI: 10.1038/sj.bjp.0701367 BindingDB Entry DOI: 10.7270/Q26M35CT
Kyoto University Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cayman Chemical Company, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human recombinant EP3 receptor expressed in HEK293 cell membranes after 120 mins by liquid scintillation counting metho...				J Med Chem 62: 4731-4741 (2019) Article DOI: 10.1021/acs.jmedchem.9b00336 BindingDB Entry DOI: 10.7270/Q22R3W32
Cayman Chemical Company, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin E2 receptor EP3 subtype (BOVINE)	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 286: 1094-102 (1998) BindingDB Entry DOI: 10.7270/Q2KK99BC
Alcon Laboratories Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to EP4 receptor (unknown origin)				J Med Chem 57: 4454-65 (2014) Article DOI: 10.1021/jm401431x BindingDB Entry DOI: 10.7270/Q2CR5VXZ
Emory University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counting				Bioorg Med Chem Lett 22: 396-401 (2011) Article DOI: 10.1016/j.bmcl.2011.10.109 BindingDB Entry DOI: 10.7270/Q27P8ZT2
Minase Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counting				Bioorg Med Chem 20: 2235-51 (2012) Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G
Minase Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin E2 receptor EP3 subtype (BOVINE)	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 286: 1094-102 (1998) BindingDB Entry DOI: 10.7270/Q2KK99BC
Alcon Laboratories Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by PDSP K_i Database									Biochim Biophys Acta 1483: 285-93 (2000) Article DOI: 10.1016/s1388-1981(99)00164-x BindingDB Entry DOI: 10.7270/Q2J964XQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
EMD Serono Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 4323-7 (2007) Article DOI: 10.1016/j.bmcl.2007.05.025 BindingDB Entry DOI: 10.7270/Q2RF5VVC
EMD Serono Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
EMD-Serono Research Institute Curated by ChEMBL					Assay Description Binding affinity at human prostaglandin EP2 receptor				Bioorg Med Chem Lett 17: 6572-5 (2007) Article DOI: 10.1016/j.bmcl.2007.09.074 BindingDB Entry DOI: 10.7270/Q29887V9
EMD-Serono Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
EMD-Serono Research Institute, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP2 receptor				Bioorg Med Chem Lett 18: 821-4 (2008) Article DOI: 10.1016/j.bmcl.2007.11.020 BindingDB Entry DOI: 10.7270/Q2W096SW
EMD-Serono Research Institute, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to EP3 receptor (unknown origin)				J Med Chem 57: 4454-65 (2014) Article DOI: 10.1021/jm401431x BindingDB Entry DOI: 10.7270/Q2CR5VXZ
Emory University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counting				Bioorg Med Chem 20: 2235-51 (2012) Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G
Minase Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by liquid scintillation counting				Bioorg Med Chem Lett 22: 396-401 (2011) Article DOI: 10.1016/j.bmcl.2011.10.109 BindingDB Entry DOI: 10.7270/Q27P8ZT2
Minase Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin E2 receptor EP1 subtype (Mus musculus (Mouse))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counting				Bioorg Med Chem 20: 2235-51 (2012) Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G
Minase Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Mus musculus (Mouse))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 20 mins by liquid scintillation counting				Bioorg Med Chem Lett 22: 396-401 (2011) Article DOI: 10.1016/j.bmcl.2011.10.109 BindingDB Entry DOI: 10.7270/Q27P8ZT2
Minase Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	9.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
EMD-Serono Research Institute, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP1 receptor				Bioorg Med Chem Lett 18: 821-4 (2008) Article DOI: 10.1016/j.bmcl.2007.11.020 BindingDB Entry DOI: 10.7270/Q2W096SW
EMD-Serono Research Institute, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	9.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by PDSP K_i Database									Biochim Biophys Acta 1483: 285-93 (2000) Article DOI: 10.1016/s1388-1981(99)00164-x BindingDB Entry DOI: 10.7270/Q2J964XQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	9.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
EMD Serono Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP1 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 4323-7 (2007) Article DOI: 10.1016/j.bmcl.2007.05.025 BindingDB Entry DOI: 10.7270/Q2RF5VVC
EMD Serono Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Mus musculus (Mouse))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by PDSP K_i Database									Br J Pharmacol 122: 217-24 (1997) Article DOI: 10.1038/sj.bjp.0701367 BindingDB Entry DOI: 10.7270/Q26M35CT
Kyoto University Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to EP1 receptor (unknown origin)				J Med Chem 57: 4454-65 (2014) Article DOI: 10.1021/jm401431x BindingDB Entry DOI: 10.7270/Q2CR5VXZ
Emory University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Mus musculus (Mouse))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by PDSP K_i Database									Br J Pharmacol 122: 217-24 (1997) Article DOI: 10.1038/sj.bjp.0701367 BindingDB Entry DOI: 10.7270/Q26M35CT
Kyoto University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Mus musculus (Mouse))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by liquid scintillation counting				Bioorg Med Chem Lett 22: 396-401 (2011) Article DOI: 10.1016/j.bmcl.2011.10.109 BindingDB Entry DOI: 10.7270/Q27P8ZT2
Minase Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin E2 receptor EP2 subtype (Mus musculus (Mouse))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting				Bioorg Med Chem 20: 2235-51 (2012) Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G
Minase Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to EP2 receptor (unknown origin) by competitive binding assay				J Med Chem 57: 4454-65 (2014) Article DOI: 10.1021/jm401431x BindingDB Entry DOI: 10.7270/Q2CR5VXZ
Emory University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin F2-alpha receptor (MOUSE)	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by PDSP K_i Database									Br J Pharmacol 122: 217-24 (1997) Article DOI: 10.1038/sj.bjp.0701367 BindingDB Entry DOI: 10.7270/Q26M35CT
Kyoto University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Prostaglandin F2-alpha receptor (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	119	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by PDSP K_i Database									Biochim Biophys Acta 1483: 285-93 (2000) Article DOI: 10.1016/s1388-1981(99)00164-x BindingDB Entry DOI: 10.7270/Q2J964XQ
					More data for this Ligand-Target Pair
Hematopoietic prostaglandin D synthase (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	307	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by PDSP K_i Database									Biochim Biophys Acta 1483: 285-93 (2000) Article DOI: 10.1016/s1388-1981(99)00164-x BindingDB Entry DOI: 10.7270/Q2J964XQ
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor (RAT)	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	2.95E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by PDSP K_i Database									J Biol Chem 257: 13570-5 (1982) BindingDB Entry DOI: 10.7270/Q22F7KXH
Kyoto University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Solute carrier family 22 member 6 (Mus musculus)	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hr				J Biol Chem 282: 23841-53 (2007) Article DOI: 10.1074/jbc.M703467200 BindingDB Entry DOI: 10.7270/Q2W95B35
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin F2-alpha receptor (BOVINE)	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 286: 1094-102 (1998) BindingDB Entry DOI: 10.7270/Q2KK99BC
Alcon Laboratories Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Thromboxane A2 receptor (MOUSE)	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Edinburgh Curated by PDSP K_i Database									Br J Pharmacol 79: 953-64 (1983) Article DOI: 10.1111/j.1476-5381.1983.tb10541.x BindingDB Entry DOI: 10.7270/Q2SX6BPF
University of Edinburgh Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Prostacyclin receptor (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Royal Postgraduate Medical School Curated by PDSP K_i Database									Br J Pharmacol 72: 435-41 (1981) Article DOI: 10.1111/j.1476-5381.1981.tb10994.x BindingDB Entry DOI: 10.7270/Q2HM56XZ
					More data for this Ligand-Target Pair
Prostacyclin receptor (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by PDSP K_i Database									Biochim Biophys Acta 1483: 285-93 (2000) Article DOI: 10.1016/s1388-1981(99)00164-x BindingDB Entry DOI: 10.7270/Q2J964XQ
					More data for this Ligand-Target Pair
Prostacyclin receptor (MOUSE)	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Royal Postgraduate Medical School Curated by PDSP K_i Database									Biochem Pharmacol 30: 2041-4 (1981) Article DOI: 10.1016/0006-2952(81)90220-3 BindingDB Entry DOI: 10.7270/Q2668BPP
					More data for this Ligand-Target Pair
Prostacyclin receptor (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to prostanoid IP receptor (unknown origin)				J Med Chem 57: 4454-65 (2014) Article DOI: 10.1021/jm401431x BindingDB Entry DOI: 10.7270/Q2CR5VXZ
Emory University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier organic anion transporter family member 2A1 (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by PDSP K_i Database									Biochim Biophys Acta 1483: 285-93 (2000) Article DOI: 10.1016/s1388-1981(99)00164-x BindingDB Entry DOI: 10.7270/Q2J964XQ
					More data for this Ligand-Target Pair
Solute carrier family 22 member 20 (Mus musculus)	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.82E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hr				J Biol Chem 282: 23841-53 (2007) Article DOI: 10.1074/jbc.M703467200 BindingDB Entry DOI: 10.7270/Q2W95B35
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier organic anion transporter family member (Danio rerio (Zebrafish))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.27E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rudjer Boskovic Institute					Assay Description In the inhibition experiments, the cells were preincubated for 20 s with test compounds, followed by a 5-min incubation with [3H]E3S (5 nM) or 30-min...				J Biol Chem 288: 33894-911 (2013) Article DOI: 10.1074/jbc.M113.518506 BindingDB Entry DOI: 10.7270/Q29Z93RK
Rudjer Boskovic Institute					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM35847 ((15S)-prostaglandin E2 \| (5Z,11alpha,13E,15S)-11,1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	n/a	2.10	n/a	n/a	n/a	n/a
Emory University School of Medicine Curated by ChEMBL					Assay Description Agonist activity at EP2 receptor (unknown origin) by functional assay				J Med Chem 57: 4454-65 (2014) Article DOI: 10.1021/jm401431x BindingDB Entry DOI: 10.7270/Q2CR5VXZ
Emory University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

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