BDBM35869 5,6-diaryl-pyrazine-2-amide derivative, 5a::5,6-diphenyl-N-(piperidin-1-yl)pyrazine-2-carboxamide::5,6-diphenyl-pyrazine-2-carboxylic acid piperidin-1-ylamide::CHEMBL389883

SMILES: O=C(NN1CCCCC1)c1cnc(-c2ccccc2)c(n1)-c1ccccc1

InChI Key: InChIKey=XIGDSDXHJVSFBZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35869   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM35869 (5,6-diaryl-pyrazine-2-amide derivative, 5a | 5,6-d...) Show SMILES O=C(NN1CCCCC1)c1cnc(-c2ccccc2)c(n1)-c1ccccc1 Show InChI InChI=1S/C22H22N4O/c27-22(25-26-14-8-3-9-15-26)19-16-23-20(17-10-4-1-5-11-17)21(24-19)18-12-6-2-7-13-18/h1-2,4-7,10-13,16H,3,8-9,14-15H2,(H,25,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Antagonist activity against human recombinant cannabinoid-1 receptor				Bioorg Med Chem Lett 19: 2990-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.037 BindingDB Entry DOI: 10.7270/Q2CN7543
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM35869 (5,6-diaryl-pyrazine-2-amide derivative, 5a | 5,6-d...) Show SMILES O=C(NN1CCCCC1)c1cnc(-c2ccccc2)c(n1)-c1ccccc1 Show InChI InChI=1S/C22H22N4O/c27-22(25-26-14-8-3-9-15-26)19-16-23-20(17-10-4-1-5-11-17)21(24-19)18-12-6-2-7-13-18/h1-2,4-7,10-13,16H,3,8-9,14-15H2,(H,25,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	766	n/a	n/a	n/a	n/a	7.4	30
AstraZeneca					Assay Description A GTP-gamma-S CB1 functional assay was used to assess the potency of the pyrazine derivatives. [35S]GTP-gamma-S binding assays were performed at 30 d...				Bioorg Med Chem 15: 4077-84 (2007) Article DOI: 10.1016/j.bmc.2007.03.075 BindingDB Entry DOI: 10.7270/Q2028PW8
					More data for this Ligand-Target Pair