BDBM35920 9,10-dihydroanthracene(DHA), 1a::9-(Aminomethyl)-9,10-dihydroanthracene::9-aminomethyl-9,10-dihydroanthracene::C-(9,10-Dihydro-anthracen-9-yl)-methylamine::CHEMBL47482
SMILES: NCC1c2ccccc2Cc2ccccc12
InChI Key: InChIKey=GEICAQNIOJFRQN-UHFFFAOYSA-N
Data: 17 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM35920 (9,10-dihydroanthracene(DHA), 1a | 9-(Aminomethyl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 20 | -10.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Virginia Commonwealth University | Assay Description Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add... | Bioorg Med Chem 17: 6496-504 (2009) Article DOI: 10.1016/j.bmc.2009.08.016 BindingDB Entry DOI: 10.7270/Q2QJ7FN6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM35920 (9,10-dihydroanthracene(DHA), 1a | 9-(Aminomethyl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Displacement of [3H]ketanserin from human 5HT2A receptor | Bioorg Med Chem Lett 18: 5268-71 (2008) Article DOI: 10.1016/j.bmcl.2008.08.059 BindingDB Entry DOI: 10.7270/Q2S46RST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM35920 (9,10-dihydroanthracene(DHA), 1a | 9-(Aminomethyl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affinity towards 5-hydroxytryptamine 2A receptor using [3H]-ketanserin | Bioorg Med Chem Lett 14: 2279-83 (2004) Article DOI: 10.1016/j.bmcl.2004.02.014 BindingDB Entry DOI: 10.7270/Q23B5ZK3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM35920 (9,10-dihydroanthracene(DHA), 1a | 9-(Aminomethyl)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affinity towards 5-hydroxytryptamine 2A receptor sites by using [3H]-Ketanserin as radioligand | Bioorg Med Chem Lett 13: 2565-8 (2003) BindingDB Entry DOI: 10.7270/Q2V40TK9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM35920 (9,10-dihydroanthracene(DHA), 1a | 9-(Aminomethyl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affinity of the compound was performed using [3H]-ketanserin as the radioligand and stably transfected NIH3T3 cells expressing the 5-hydroxyt... | J Med Chem 45: 1656-64 (2002) BindingDB Entry DOI: 10.7270/Q23T9GJ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM35920 (9,10-dihydroanthracene(DHA), 1a | 9-(Aminomethyl)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affinity against 5-hydroxytryptamine 2A receptor expressed NIH3T3 cells using [3H]-ketanserin | Bioorg Med Chem Lett 11: 563-6 (2001) BindingDB Entry DOI: 10.7270/Q29S1Q80 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM35920 (9,10-dihydroanthracene(DHA), 1a | 9-(Aminomethyl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2A receptor expressed NIH3T3 cells | Bioorg Med Chem Lett 11: 655-8 (2001) BindingDB Entry DOI: 10.7270/Q2H994F8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM35920 (9,10-dihydroanthracene(DHA), 1a | 9-(Aminomethyl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Displacement of [3H]ketanserin from 5HT2A receptor expressed in NIH3T3 cells | J Med Chem 51: 6808-28 (2008) Article DOI: 10.1021/jm800771x BindingDB Entry DOI: 10.7270/Q2KD1ZTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM35920 (9,10-dihydroanthracene(DHA), 1a | 9-(Aminomethyl)-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine from 5HT2C receptor | J Med Chem 51: 6808-28 (2008) Article DOI: 10.1021/jm800771x BindingDB Entry DOI: 10.7270/Q2KD1ZTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (5HT2C) (Mus musculus (Mouse)) | BDBM35920 (9,10-dihydroanthracene(DHA), 1a | 9-(Aminomethyl)-...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affinity to 5-hydroxytryptamine 2C receptor using [3H]Mesulergine as radioligand in stably transfected NIH3T3 cells | Bioorg Med Chem Lett 11: 655-8 (2001) BindingDB Entry DOI: 10.7270/Q2H994F8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H1 receptor (Homo sapiens (Human)) | BDBM35920 (9,10-dihydroanthracene(DHA), 1a | 9-(Aminomethyl)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 197 | -9.14 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Virginia Commonwealth University | Assay Description Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add... | Bioorg Med Chem 17: 6496-504 (2009) Article DOI: 10.1016/j.bmc.2009.08.016 BindingDB Entry DOI: 10.7270/Q2QJ7FN6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Mus musculus (Mouse)) | BDBM35920 (9,10-dihydroanthracene(DHA), 1a | 9-(Aminomethyl)-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affinity to Dopamine receptor D2 using [3H]spiperone as radioligand in stably transfected NIH3T3 cells | Bioorg Med Chem Lett 11: 655-8 (2001) BindingDB Entry DOI: 10.7270/Q2H994F8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM35920 (9,10-dihydroanthracene(DHA), 1a | 9-(Aminomethyl)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor | J Med Chem 51: 6808-28 (2008) Article DOI: 10.1021/jm800771x BindingDB Entry DOI: 10.7270/Q2KD1ZTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
SLC6A4 (MOUSE) | BDBM35920 (9,10-dihydroanthracene(DHA), 1a | 9-(Aminomethyl)-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affinity to Serotonin transporter using [3H]-paroxetine as radioligand in stably transfected NIH3T3 cells | Bioorg Med Chem Lett 11: 655-8 (2001) BindingDB Entry DOI: 10.7270/Q2H994F8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Norepinephrine transporter (MOUSE) | BDBM35920 (9,10-dihydroanthracene(DHA), 1a | 9-(Aminomethyl)-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affinity to Norepinephrine transporter using [3H]-nisoxatine as radioligand in stably transfected NIH3T3 cells | Bioorg Med Chem Lett 11: 655-8 (2001) BindingDB Entry DOI: 10.7270/Q2H994F8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM35920 (9,10-dihydroanthracene(DHA), 1a | 9-(Aminomethyl)-...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Displacement of [3H]nisoxitine from NET | J Med Chem 51: 6808-28 (2008) Article DOI: 10.1021/jm800771x BindingDB Entry DOI: 10.7270/Q2KD1ZTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM35920 (9,10-dihydroanthracene(DHA), 1a | 9-(Aminomethyl)-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Displacement of [3H]paroxitine from SERT | J Med Chem 51: 6808-28 (2008) Article DOI: 10.1021/jm800771x BindingDB Entry DOI: 10.7270/Q2KD1ZTR | |||||||||||
More data for this Ligand-Target Pair |