BDBM35922 (9,10-Dihydro-anthracen-9-ylmethyl)-dimethyl-amine::1-(9,10-dihydroanthracen-9-yl)-N,N-dimethylmethanamine::9,10-dihydroanthracene(DHA), 1c::CHEMBL160933
SMILES: CN(C)CC1c2ccccc2Cc2ccccc12
InChI Key: InChIKey=FCRIMCQUUZFBDN-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H1 receptor (Homo sapiens (Human)) | BDBM35922 ((9,10-Dihydro-anthracen-9-ylmethyl)-dimethyl-amine...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 25 | -10.4 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Virginia Commonwealth University | Assay Description Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add... | Bioorg Med Chem 17: 6496-504 (2009) Article DOI: 10.1016/j.bmc.2009.08.016 BindingDB Entry DOI: 10.7270/Q2QJ7FN6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM35922 ((9,10-Dihydro-anthracen-9-ylmethyl)-dimethyl-amine...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 540 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2A receptor expressed NIH3T3 cells | Bioorg Med Chem Lett 11: 655-8 (2001) BindingDB Entry DOI: 10.7270/Q2H994F8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM35922 ((9,10-Dihydro-anthracen-9-ylmethyl)-dimethyl-amine...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 540 | -8.49 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Virginia Commonwealth University | Assay Description Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add... | Bioorg Med Chem 17: 6496-504 (2009) Article DOI: 10.1016/j.bmc.2009.08.016 BindingDB Entry DOI: 10.7270/Q2QJ7FN6 | |||||||||||
More data for this Ligand-Target Pair |