null

SMILES: NC(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCC2)ccc1F

InChI Key: InChIKey=VQJVYLHNJCVCIV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 359721   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM359721 (US10435355, Example 5 | US9822068, 5 | [3-(3-carba...) Show SMILES NC(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCC2)ccc1F Show InChI InChI=1S/C19H19FN2O3/c20-17-9-8-15(25-19(24)22-14-6-1-2-7-14)11-16(17)12-4-3-5-13(10-12)18(21)23/h3-5,8-11,14H,1-2,6-7H2,(H2,21,23)(H,22,24)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California; Fondazione Istituto Italiano di Technologia US Patent					Assay Description Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...				US Patent US9822068 (2017) BindingDB Entry DOI: 10.7270/Q2Q242HW
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM359721 (US10435355, Example 5 | US9822068, 5 | [3-(3-carba...) Show SMILES NC(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCC2)ccc1F Show InChI InChI=1S/C19H19FN2O3/c20-17-9-8-15(25-19(24)22-14-6-1-2-7-14)11-16(17)12-4-3-5-13(10-12)18(21)23/h3-5,8-11,14H,1-2,6-7H2,(H2,21,23)(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.840	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Human recombinant FAAH was obtained from a HEK-293 cell line stably overexpressing human FAAH-1 enzyme. Cells were grown in Dulbecco's Modified E...				US Patent US10435355 (2019) BindingDB Entry DOI: 10.7270/Q29C70TM
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM359721 (US10435355, Example 5 | US9822068, 5 | [3-(3-carba...) Show SMILES NC(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCC2)ccc1F Show InChI InChI=1S/C19H19FN2O3/c20-17-9-8-15(25-19(24)22-14-6-1-2-7-14)11-16(17)12-4-3-5-13(10-12)18(21)23/h3-5,8-11,14H,1-2,6-7H2,(H2,21,23)(H,22,24)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...				US Patent US10435355 (2019) BindingDB Entry DOI: 10.7270/Q29C70TM
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM359721 (US10435355, Example 5 | US9822068, 5 | [3-(3-carba...) Show SMILES NC(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCC2)ccc1F Show InChI InChI=1S/C19H19FN2O3/c20-17-9-8-15(25-19(24)22-14-6-1-2-7-14)11-16(17)12-4-3-5-13(10-12)18(21)23/h3-5,8-11,14H,1-2,6-7H2,(H2,21,23)(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.840	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California; Fondazione Istituto Italiano di Technologia US Patent					Assay Description Human recombinant FAAH was obtained from a HEK-293 cell line stably overexpressing human FAAH-1 enzyme. Cells were grown in Dulbecco's Modified E...				US Patent US9822068 (2017) BindingDB Entry DOI: 10.7270/Q2Q242HW
					More data for this Ligand-Target Pair