BDBM359727 US10435355, Example 11::US9822068, 11::[4-(difluoromethoxy)-3-(3- methylsulfonylphenyl) phenyl]N- cyclohexylcarbamate

SMILES: CS(=O)(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCCC2)ccc1OC(F)F

InChI Key: InChIKey=MYHKIGBMSJTKDP-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 359727   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM359727 (US10435355, Example 11 | US9822068, 11 | [4-(diflu...) Show SMILES CS(=O)(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCCC2)ccc1OC(F)F Show InChI InChI=1S/C21H23F2NO5S/c1-30(26,27)17-9-5-6-14(12-17)18-13-16(10-11-19(18)29-20(22)23)28-21(25)24-15-7-3-2-4-8-15/h5-6,9-13,15,20H,2-4,7-8H2,1H3,(H,24,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California; Fondazione Istituto Italiano di Technologia US Patent					Assay Description Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...				US Patent US9822068 (2017) BindingDB Entry DOI: 10.7270/Q2Q242HW
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM359727 (US10435355, Example 11 | US9822068, 11 | [4-(diflu...) Show SMILES CS(=O)(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCCC2)ccc1OC(F)F Show InChI InChI=1S/C21H23F2NO5S/c1-30(26,27)17-9-5-6-14(12-17)18-13-16(10-11-19(18)29-20(22)23)28-21(25)24-15-7-3-2-4-8-15/h5-6,9-13,15,20H,2-4,7-8H2,1H3,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Human recombinant FAAH was obtained from a HEK-293 cell line stably overexpressing human FAAH-1 enzyme. Cells were grown in Dulbecco's Modified E...				US Patent US10435355 (2019) BindingDB Entry DOI: 10.7270/Q29C70TM
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM359727 (US10435355, Example 11 | US9822068, 11 | [4-(diflu...) Show SMILES CS(=O)(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCCC2)ccc1OC(F)F Show InChI InChI=1S/C21H23F2NO5S/c1-30(26,27)17-9-5-6-14(12-17)18-13-16(10-11-19(18)29-20(22)23)28-21(25)24-15-7-3-2-4-8-15/h5-6,9-13,15,20H,2-4,7-8H2,1H3,(H,24,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...				US Patent US10435355 (2019) BindingDB Entry DOI: 10.7270/Q29C70TM
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM359727 (US10435355, Example 11 | US9822068, 11 | [4-(diflu...) Show SMILES CS(=O)(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCCC2)ccc1OC(F)F Show InChI InChI=1S/C21H23F2NO5S/c1-30(26,27)17-9-5-6-14(12-17)18-13-16(10-11-19(18)29-20(22)23)28-21(25)24-15-7-3-2-4-8-15/h5-6,9-13,15,20H,2-4,7-8H2,1H3,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California; Fondazione Istituto Italiano di Technologia US Patent					Assay Description Human recombinant FAAH was obtained from a HEK-293 cell line stably overexpressing human FAAH-1 enzyme. Cells were grown in Dulbecco's Modified E...				US Patent US9822068 (2017) BindingDB Entry DOI: 10.7270/Q2Q242HW
					More data for this Ligand-Target Pair