BDBM359728 US10435355, Example 12::US9822068, 12::[3-(3-carbamoylphenyl)-5- fluoro-phenyl]N- cyclohexylcarbamate

SMILES: NC(=O)c1cccc(c1)-c1cc(F)cc(OC(=O)NC2CCCCC2)c1

InChI Key: InChIKey=UCDFUDXERZJFIY-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 359728   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM359728 (US10435355, Example 12 | US9822068, 12 | [3-(3-car...) Show SMILES NC(=O)c1cccc(c1)-c1cc(F)cc(OC(=O)NC2CCCCC2)c1 Show InChI InChI=1S/C20H21FN2O3/c21-16-10-15(13-5-4-6-14(9-13)19(22)24)11-18(12-16)26-20(25)23-17-7-2-1-3-8-17/h4-6,9-12,17H,1-3,7-8H2,(H2,22,24)(H,23,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California; Fondazione Istituto Italiano di Technologia US Patent					Assay Description Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...				US Patent US9822068 (2017) BindingDB Entry DOI: 10.7270/Q2Q242HW
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM359728 (US10435355, Example 12 | US9822068, 12 | [3-(3-car...) Show SMILES NC(=O)c1cccc(c1)-c1cc(F)cc(OC(=O)NC2CCCCC2)c1 Show InChI InChI=1S/C20H21FN2O3/c21-16-10-15(13-5-4-6-14(9-13)19(22)24)11-18(12-16)26-20(25)23-17-7-2-1-3-8-17/h4-6,9-12,17H,1-3,7-8H2,(H2,22,24)(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.870	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Human recombinant FAAH was obtained from a HEK-293 cell line stably overexpressing human FAAH-1 enzyme. Cells were grown in Dulbecco's Modified E...				US Patent US10435355 (2019) BindingDB Entry DOI: 10.7270/Q29C70TM
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM359728 (US10435355, Example 12 | US9822068, 12 | [3-(3-car...) Show SMILES NC(=O)c1cccc(c1)-c1cc(F)cc(OC(=O)NC2CCCCC2)c1 Show InChI InChI=1S/C20H21FN2O3/c21-16-10-15(13-5-4-6-14(9-13)19(22)24)11-18(12-16)26-20(25)23-17-7-2-1-3-8-17/h4-6,9-12,17H,1-3,7-8H2,(H2,22,24)(H,23,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...				US Patent US10435355 (2019) BindingDB Entry DOI: 10.7270/Q29C70TM
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM359728 (US10435355, Example 12 | US9822068, 12 | [3-(3-car...) Show SMILES NC(=O)c1cccc(c1)-c1cc(F)cc(OC(=O)NC2CCCCC2)c1 Show InChI InChI=1S/C20H21FN2O3/c21-16-10-15(13-5-4-6-14(9-13)19(22)24)11-18(12-16)26-20(25)23-17-7-2-1-3-8-17/h4-6,9-12,17H,1-3,7-8H2,(H2,22,24)(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.870	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California; Fondazione Istituto Italiano di Technologia US Patent					Assay Description Human recombinant FAAH was obtained from a HEK-293 cell line stably overexpressing human FAAH-1 enzyme. Cells were grown in Dulbecco's Modified E...				US Patent US9822068 (2017) BindingDB Entry DOI: 10.7270/Q2Q242HW
					More data for this Ligand-Target Pair