BDBM36024 (R)-(-)-phenylephrine::PHENYLEPHRINE::Phenylephrine,(-)

SMILES: C[NH2+]C[C@H](O)c1cccc(O)c1

InChI Key: InChIKey=SONNWYBIRXJNDC-VIFPVBQESA-O

Data: 18 KI  4 ITC

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 36024   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM36024 ((R)-(-)-phenylephrine | PHENYLEPHRINE | Phenylephr...) Show SMILES C[NH2+]C[C@H](O)c1cccc(O)c1 Show InChI InChI=1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/p+1/t9-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UnWersity of Misscuri Curated by PDSP Ki Database									J Pharmacol Exp Ther 241: 875-81 (1987) BindingDB Entry DOI: 10.7270/Q29885JF
					More data for this Ligand-Target Pair
adrenergic Alpha1 (Dog)	BDBM36024 ((R)-(-)-phenylephrine | PHENYLEPHRINE | Phenylephr...) Show SMILES C[NH2+]C[C@H](O)c1cccc(O)c1 Show InChI InChI=1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/p+1/t9-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	213	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UnWersity of Misscuri Curated by PDSP Ki Database									J Pharmacol Exp Ther 241: 875-81 (1987) BindingDB Entry DOI: 10.7270/Q29885JF
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM36024 ((R)-(-)-phenylephrine | PHENYLEPHRINE | Phenylephr...) Show SMILES C[NH2+]C[C@H](O)c1cccc(O)c1 Show InChI InChI=1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/p+1/t9-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP Ki Database									Life Sci 19: 69-76 (1976) Article DOI: 10.1016/0024-3205(76)90375-1 BindingDB Entry DOI: 10.7270/Q23B5XNK
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM36024 ((R)-(-)-phenylephrine | PHENYLEPHRINE | Phenylephr...) Show SMILES C[NH2+]C[C@H](O)c1cccc(O)c1 Show InChI InChI=1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/p+1/t9-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UnWersity of Misscuri Curated by PDSP Ki Database									J Pharmacol Exp Ther 241: 875-81 (1987) BindingDB Entry DOI: 10.7270/Q29885JF
					More data for this Ligand-Target Pair
Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM36024 ((R)-(-)-phenylephrine | PHENYLEPHRINE | Phenylephr...) Show SMILES C[NH2+]C[C@H](O)c1cccc(O)c1 Show InChI InChI=1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/p+1/t9-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from adrenergic alpha 2 receptor of rat cerebral cortical membranes				J Med Chem 36: 3947-55 (1994) BindingDB Entry DOI: 10.7270/Q2QC044C
					More data for this Ligand-Target Pair
adrenergic Alpha1 (Dog)	BDBM36024 ((R)-(-)-phenylephrine | PHENYLEPHRINE | Phenylephr...) Show SMILES C[NH2+]C[C@H](O)c1cccc(O)c1 Show InChI InChI=1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/p+1/t9-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	901	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UnWersity of Misscuri Curated by PDSP Ki Database									J Pharmacol Exp Ther 241: 875-81 (1987) BindingDB Entry DOI: 10.7270/Q29885JF
					More data for this Ligand-Target Pair
adrenergic Alpha2 (RAT)	BDBM36024 ((R)-(-)-phenylephrine | PHENYLEPHRINE | Phenylephr...) Show SMILES C[NH2+]C[C@H](O)c1cccc(O)c1 Show InChI InChI=1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/p+1/t9-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by PDSP Ki Database									J Pharmacol Exp Ther 241: 1092-8 (1987) BindingDB Entry DOI: 10.7270/Q2F18X7B
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM36024 ((R)-(-)-phenylephrine | PHENYLEPHRINE | Phenylephr...) Show SMILES C[NH2+]C[C@H](O)c1cccc(O)c1 Show InChI InChI=1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/p+1/t9-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP Ki Database									Eur J Pharmacol 55: 323-6 (1979) Article DOI: 10.1016/0014-2999(79)90202-4 BindingDB Entry DOI: 10.7270/Q2KD1WC3
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM36024 ((R)-(-)-phenylephrine | PHENYLEPHRINE | Phenylephr...) Show SMILES C[NH2+]C[C@H](O)c1cccc(O)c1 Show InChI InChI=1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/p+1/t9-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	1.44E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by PDSP Ki Database									J Biol Chem 266: 6365-9 (1991) BindingDB Entry DOI: 10.7270/Q2X928SG
					More data for this Ligand-Target Pair
adrenergic Alpha2 (RAT)	BDBM36024 ((R)-(-)-phenylephrine | PHENYLEPHRINE | Phenylephr...) Show SMILES C[NH2+]C[C@H](O)c1cccc(O)c1 Show InChI InChI=1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/p+1/t9-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	1.47E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by PDSP Ki Database									J Pharmacol Exp Ther 241: 1092-8 (1987) BindingDB Entry DOI: 10.7270/Q2F18X7B
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM36024 ((R)-(-)-phenylephrine | PHENYLEPHRINE | Phenylephr...) Show SMILES C[NH2+]C[C@H](O)c1cccc(O)c1 Show InChI InChI=1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/p+1/t9-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Displacement of [3H]WB-4101 from adrenergic alpha 1 receptor of rat cerebral cortical membranes				J Med Chem 36: 3947-55 (1994) BindingDB Entry DOI: 10.7270/Q2QC044C
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM36024 ((R)-(-)-phenylephrine | PHENYLEPHRINE | Phenylephr...) Show SMILES C[NH2+]C[C@H](O)c1cccc(O)c1 Show InChI InChI=1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/p+1/t9-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP Ki Database									Life Sci 19: 69-76 (1976) Article DOI: 10.1016/0024-3205(76)90375-1 BindingDB Entry DOI: 10.7270/Q23B5XNK
					More data for this Ligand-Target Pair
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat))	BDBM36024 ((R)-(-)-phenylephrine | PHENYLEPHRINE | Phenylephr...) Show SMILES C[NH2+]C[C@H](O)c1cccc(O)c1 Show InChI InChI=1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/p+1/t9-/m0/s1	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by PDSP Ki Database									J Biol Chem 266: 6365-9 (1991) BindingDB Entry DOI: 10.7270/Q2X928SG
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM36024 ((R)-(-)-phenylephrine | PHENYLEPHRINE | Phenylephr...) Show SMILES C[NH2+]C[C@H](O)c1cccc(O)c1 Show InChI InChI=1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/p+1/t9-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP Ki Database									Mol Pharmacol 12: 568-80 (1976) BindingDB Entry DOI: 10.7270/Q2ZK5F5P
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM36024 ((R)-(-)-phenylephrine | PHENYLEPHRINE | Phenylephr...) Show SMILES C[NH2+]C[C@H](O)c1cccc(O)c1 Show InChI InChI=1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/p+1/t9-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP Ki Database									Mol Pharmacol 12: 568-80 (1976) BindingDB Entry DOI: 10.7270/Q2ZK5F5P
					More data for this Ligand-Target Pair
ADRA1B (C.H.O.)	BDBM36024 ((R)-(-)-phenylephrine | PHENYLEPHRINE | Phenylephr...) Show SMILES C[NH2+]C[C@H](O)c1cccc(O)c1 Show InChI InChI=1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/p+1/t9-/m0/s1	Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Children's Medical Research Center Curated by PDSP Ki Database									Eur J Pharmacol 268: 399-407 (1994) Article DOI: 10.1016/0922-4106(94)90065-5 BindingDB Entry DOI: 10.7270/Q26W98KS
					More data for this Ligand-Target Pair
Cerebral cortex alpha adrenergic receptor (CALF)	BDBM36024 ((R)-(-)-phenylephrine | PHENYLEPHRINE | Phenylephr...) Show SMILES C[NH2+]C[C@H](O)c1cccc(O)c1 Show InChI InChI=1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/p+1/t9-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by PDSP Ki Database									J Biol Chem 266: 6365-9 (1991) BindingDB Entry DOI: 10.7270/Q2X928SG
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Rattus norvegicus (Rat))	BDBM36024 ((R)-(-)-phenylephrine | PHENYLEPHRINE | Phenylephr...) Show SMILES C[NH2+]C[C@H](O)c1cccc(O)c1 Show InChI InChI=1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/p+1/t9-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Displacement of [3H]dihydroalprenolol from adrenergic beta 1 receptor of rat cerebral cortical membranes				J Med Chem 36: 3947-55 (1994) BindingDB Entry DOI: 10.7270/Q2QC044C
					More data for this Ligand-Target Pair

Activity Spreadsheet -- ITC Data from BindingDB

Found 4 hits for monomerid = 36024

Cell (A)	Syringe (B)	Cell Links	Syringe Links	Cell + Syr Links	ΔG° kcal/mole	-TΔS° kcal/mole	ΔH° kcal/mole	log K	pH	Temp °C
BDBM4	BDBM36024	CHEBI MMDB PC cid PC sid PDB	CHEBI KEGG PC cid PC sid		-0.836	7.19	-8.12	0.610	6.90	24.9
NIST					J Am Chem Soc 117: 8830-40 (1995)
BDBM4	BDBM36024	CHEBI MMDB PC cid PC sid PDB	CHEBI KEGG PC cid PC sid		-0.764	5.25	-5.97	0.560	5	24.9
NIST					J Am Chem Soc 117: 8830-40 (1995)
BDBM11	BDBM36024	CHEBI KEGG MMDB PC cid PC sid PDB	CHEBI KEGG PC cid PC sid		-2.27	2.36	-4.64	1.67	6.90	24.9
NIST					J Am Chem Soc 117: 8830-40 (1995)
BDBM11	BDBM36024	CHEBI KEGG MMDB PC cid PC sid PDB	CHEBI KEGG PC cid PC sid		-2.17	3.06	-5.23	1.59	5	24.9
NIST					J Am Chem Soc 117: 8830-40 (1995)