BDBM36137 Cbz-L-Asp
SMILES: OC(=O)C[C@H](NC(=O)OCc1ccccc1)C(O)=O
InChI Key: InChIKey=XYXYXSKSTZAEJW-VIFPVBQESA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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DNA topoisomerase II (Homo sapiens (Human)) | BDBM36137 (Cbz-L-Asp) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Key Laboratory of Pharmaceutical Quality Control of Hebei Province, College of Pharmaceutical Sciences, Hebei University, Baoding 071002, China. Curated by ChEMBL | Assay Description Inhibition of human recombinant topoisomerase-2alpha expressed in Escherichia coli assessed as decrease in relaxation of supercoiled DNA pBR322 after... | Bioorg Med Chem 25: 3116-3126 (2017) Article DOI: 10.1016/j.bmc.2017.03.065 BindingDB Entry DOI: 10.7270/Q22Z180K | |||||||||||
More data for this Ligand-Target Pair |