BDBM362174 US9833448, Example 17
SMILES: Fc1cccc([C@@H]2C[C@H](NC(=O)c3cnc4C[C@]5(Cc4c3)C(=O)Nc3ncccc53)C(=O)N(CC3CCC3)C2)c1F
InChI Key: InChIKey=SUKIQFSJOWYYTQ-XMBZSLMXSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Calcitonin receptor-like receptor (CLR) (Homo sapiens (Human)) | BDBM362174 (US9833448, Example 17) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | UniChem | US Patent | 0.0550 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 μM isobutyl-methylxanthine. Cells were then plated in a 384-wel... | US Patent US9833448 (2017) BindingDB Entry DOI: 10.7270/Q2BP052K | |||||||||||
More data for this Ligand-Target Pair |