BDBM362182 USRE47267, Compound 137

SMILES: CCOC(=O)c1cc(on1)C(=O)CSc1ccc(cn1)C(=O)Nc1ccc(F)cc1

InChI Key: InChIKey=GKDYRLGAGFSOMN-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 362182   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM362182 (USRE47267, Compound 137) Show SMILES CCOC(=O)c1cc(on1)C(=O)CSc1ccc(cn1)C(=O)Nc1ccc(F)cc1 Show InChI InChI=1S/C20H16FN3O5S/c1-2-28-20(27)15-9-17(29-24-15)16(25)11-30-18-8-3-12(10-22-18)19(26)23-14-6-4-13(21)5-7-14/h3-10H,2,11H2,1H3,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Syntrix Biosystems, Inc. US Patent					Assay Description The assay is a Ca2+ mobilization assay that measures changes in intracellular Ca2+ with a FlexStation II scanning fluorometer using a FLIPR-3 Calcium...				US Patent USRE47267 (2019) BindingDB Entry DOI: 10.7270/Q2GF0WSH
					More data for this Ligand-Target Pair