BDBM3623 US8524699, 28
SMILES: COCCN1CCN(CC1)c1cc(ncn1)-n1[nH]cc(-c2cccnc2)c1=O
InChI Key: InChIKey=KOLAVCBBJLWGOM-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hypoxia-inducible factor prolyl hydroxylase 4 (HIF) (Homo sapiens (Human)) | BDBM3623 (US8524699, 28) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 890 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bayer Intellectual Property GmbH US Patent | Assay Description In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors. | US Patent US8524699 (2013) BindingDB Entry DOI: 10.7270/Q2TB15J4 | |||||||||||
More data for this Ligand-Target Pair |