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SMILES: Cc1nc(N)nc(N2CCC[C@H]2c2nc3ccc(F)c(-c4cnn(C)c4)c3c(=O)n2-c2ccccc2)c1C#N

InChI Key: InChIKey=BQKRPXCJIYXLOR-QFIPXVFZSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 362680   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM362680 (US9840498, 6) Show SMILES Cc1nc(N)nc(N2CCC[C@H]2c2nc3ccc(F)c(-c4cnn(C)c4)c3c(=O)n2-c2ccccc2)c1C#N |r| Show InChI InChI=1S/C28H24FN9O/c1-16-19(13-30)25(35-28(31)33-16)37-12-6-9-22(37)26-34-21-11-10-20(29)23(17-14-32-36(2)15-17)24(21)27(39)38(26)18-7-4-3-5-8-18/h3-5,7-8,10-11,14-15,22H,6,9,12H2,1-2H3,(H2,31,33,35)/t22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM362680 (US9840498, 6) Show SMILES Cc1nc(N)nc(N2CCC[C@H]2c2nc3ccc(F)c(-c4cnn(C)c4)c3c(=O)n2-c2ccccc2)c1C#N |r| Show InChI InChI=1S/C28H24FN9O/c1-16-19(13-30)25(35-28(31)33-16)37-12-6-9-22(37)26-34-21-11-10-20(29)23(17-14-32-36(2)15-17)24(21)27(39)38(26)18-7-4-3-5-8-18/h3-5,7-8,10-11,14-15,22H,6,9,12H2,1-2H3,(H2,31,33,35)/t22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362680 (US9840498, 6) Show SMILES Cc1nc(N)nc(N2CCC[C@H]2c2nc3ccc(F)c(-c4cnn(C)c4)c3c(=O)n2-c2ccccc2)c1C#N |r| Show InChI InChI=1S/C28H24FN9O/c1-16-19(13-30)25(35-28(31)33-16)37-12-6-9-22(37)26-34-21-11-10-20(29)23(17-14-32-36(2)15-17)24(21)27(39)38(26)18-7-4-3-5-8-18/h3-5,7-8,10-11,14-15,22H,6,9,12H2,1-2H3,(H2,31,33,35)/t22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair