null

SMILES: COc1ncc(s1)-c1c(F)ccc2nc([C@@H]3C[C@H](O)CN3c3nc(N)nc(C)c3C#N)n(-c3ccccc3)c(=O)c12

InChI Key: InChIKey=OPNRYAQJSHIIBL-JXFKEZNVSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 362683   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM362683 (US9840498, 9) Show SMILES COc1ncc(s1)-c1c(F)ccc2nc([C@@H]3C[C@H](O)CN3c3nc(N)nc(C)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C28H23FN8O3S/c1-14-17(11-30)24(35-27(31)33-14)36-13-16(38)10-20(36)25-34-19-9-8-18(29)22(21-12-32-28(40-2)41-21)23(19)26(39)37(25)15-6-4-3-5-7-15/h3-9,12,16,20,38H,10,13H2,1-2H3,(H2,31,33,35)/t16-,20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM362683 (US9840498, 9) Show SMILES COc1ncc(s1)-c1c(F)ccc2nc([C@@H]3C[C@H](O)CN3c3nc(N)nc(C)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C28H23FN8O3S/c1-14-17(11-30)24(35-27(31)33-14)36-13-16(38)10-20(36)25-34-19-9-8-18(29)22(21-12-32-28(40-2)41-21)23(19)26(39)37(25)15-6-4-3-5-7-15/h3-9,12,16,20,38H,10,13H2,1-2H3,(H2,31,33,35)/t16-,20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362683 (US9840498, 9) Show SMILES COc1ncc(s1)-c1c(F)ccc2nc([C@@H]3C[C@H](O)CN3c3nc(N)nc(C)c3C#N)n(-c3ccccc3)c(=O)c12 |r| Show InChI InChI=1S/C28H23FN8O3S/c1-14-17(11-30)24(35-27(31)33-14)36-13-16(38)10-20(36)25-34-19-9-8-18(29)22(21-12-32-28(40-2)41-21)23(19)26(39)37(25)15-6-4-3-5-7-15/h3-9,12,16,20,38H,10,13H2,1-2H3,(H2,31,33,35)/t16-,20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair