null

SMILES: Cc1nc(N)nc(N2C[C@@H](O)C[C@H]2c2nc3cccc(-c4cncnc4)c3c(=O)n2-c2ccccc2)c1C#N

InChI Key: InChIKey=BKXGAUFMADTWDC-CVDCTZTESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 362699   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM362699 (US9840498, 26) Show SMILES Cc1nc(N)nc(N2C[C@@H](O)C[C@H]2c2nc3cccc(-c4cncnc4)c3c(=O)n2-c2ccccc2)c1C#N |r| Show InChI InChI=1S/C28H23N9O2/c1-16-21(11-29)25(35-28(30)33-16)36-14-19(38)10-23(36)26-34-22-9-5-8-20(17-12-31-15-32-13-17)24(22)27(39)37(26)18-6-3-2-4-7-18/h2-9,12-13,15,19,23,38H,10,14H2,1H3,(H2,30,33,35)/t19-,23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM362699 (US9840498, 26) Show SMILES Cc1nc(N)nc(N2C[C@@H](O)C[C@H]2c2nc3cccc(-c4cncnc4)c3c(=O)n2-c2ccccc2)c1C#N |r| Show InChI InChI=1S/C28H23N9O2/c1-16-21(11-29)25(35-28(30)33-16)36-14-19(38)10-23(36)26-34-22-9-5-8-20(17-12-31-15-32-13-17)24(22)27(39)37(26)18-6-3-2-4-7-18/h2-9,12-13,15,19,23,38H,10,14H2,1H3,(H2,30,33,35)/t19-,23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362699 (US9840498, 26) Show SMILES Cc1nc(N)nc(N2C[C@@H](O)C[C@H]2c2nc3cccc(-c4cncnc4)c3c(=O)n2-c2ccccc2)c1C#N |r| Show InChI InChI=1S/C28H23N9O2/c1-16-21(11-29)25(35-28(30)33-16)36-14-19(38)10-23(36)26-34-22-9-5-8-20(17-12-31-15-32-13-17)24(22)27(39)37(26)18-6-3-2-4-7-18/h2-9,12-13,15,19,23,38H,10,14H2,1H3,(H2,30,33,35)/t19-,23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair