BDBM36340 4-{2-trans-(4-Amino-cyclohexylamino)-6-[4-(piperidine-1-carbonyl)-phenylamino]-purin-9-yl}-benzoic acid, 8::CID24762170
SMILES: N[C@H]1CC[C@@H](CC1)Nc1nc(Nc2ccc(cc2)C(=O)N2CCCCC2)c2ncn(-c3ccc(cc3)C(O)=O)c2n1
InChI Key: InChIKey=GZNMYBJDBYQBKG-AFARHQOCSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Calcium-dependent protein kinase 1 (Plasmodium Falciparum) | BDBM36340 (4-{2-trans-(4-Amino-cyclohexylamino)-6-[4-(piperid...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | 7.5 | 24 |
The Scripps Research Institute | Nat Chem Biol 4: 347-56 (2008) Article DOI: 10.1038/nchembio.87 BindingDB Entry DOI: 10.7270/Q2TB1573 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calcium-dependent protein kinase 1 (Plasmodium Falciparum) | BDBM36340 (4-{2-trans-(4-Amino-cyclohexylamino)-6-[4-(piperid...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | 7.5 | 24 |
The Scripps Research Institute | Assay Description The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft... | Nat Chem Biol 4: 347-56 (2008) Article DOI: 10.1038/nchembio.87 BindingDB Entry DOI: 10.7270/Q2TB1573 | |||||||||||
More data for this Ligand-Target Pair |