BDBM36483 (S)-6-acetamido-2-(2-((S)-2-acetamido-4-methylpentanamido)acetamido)-N-(4-methyl-2-oxo-2H-chromen-7-yl)hexanamide, 3::CID10460379
SMILES: CC(C)C[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCNC(C)=O)C(=O)Nc1ccc2c(C)cc(=O)oc2c1
InChI Key: InChIKey=YLJRILGAXBHXDZ-GOTSBHOMSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM36483 ((S)-6-acetamido-2-(2-((S)-2-acetamido-4-methylpent...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.18E+3 | n/a | n/a | n/a | n/a | 7.4 | 0 |
Dana-Farber Cancer Institute | Assay Description For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add... | Nat Chem Biol 6: 238-243 (2010) Article DOI: 10.1038/nchembio.313 BindingDB Entry DOI: 10.7270/Q2C53J66 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 9 (Homo sapiens (Human)) | BDBM36483 ((S)-6-acetamido-2-(2-((S)-2-acetamido-4-methylpent...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.34E+3 | n/a | n/a | n/a | n/a | 7.4 | 0 |
Dana-Farber Cancer Institute | Assay Description For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add... | Nat Chem Biol 6: 238-243 (2010) Article DOI: 10.1038/nchembio.313 BindingDB Entry DOI: 10.7270/Q2C53J66 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 7 (Homo sapiens (Human)) | BDBM36483 ((S)-6-acetamido-2-(2-((S)-2-acetamido-4-methylpent...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.29E+3 | n/a | n/a | n/a | n/a | 7.4 | 0 |
Dana-Farber Cancer Institute | Assay Description For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add... | Nat Chem Biol 6: 238-243 (2010) Article DOI: 10.1038/nchembio.313 BindingDB Entry DOI: 10.7270/Q2C53J66 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 5 (Homo sapiens (Human)) | BDBM36483 ((S)-6-acetamido-2-(2-((S)-2-acetamido-4-methylpent...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.04E+3 | n/a | n/a | n/a | n/a | 7.4 | 0 |
Dana-Farber Cancer Institute | Assay Description For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add... | Nat Chem Biol 6: 238-243 (2010) Article DOI: 10.1038/nchembio.313 BindingDB Entry DOI: 10.7270/Q2C53J66 | |||||||||||
More data for this Ligand-Target Pair |