null

SMILES: OC(=O)C[C@@H](NC(=O)c1cccn(Cc2ccc(F)c(F)c2)c1=O)c1ccc(s1)-c1c[nH]c2ncccc12

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 366092   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-phosphoinositide-dependent protein kinase 1 [51-360] (Homo sapiens (Human))	BDBM366092 (US9873693, Compound 15 | US9873693, Compound 234) Show SMILES OC(=O)C[C@@H](NC(=O)c1cccn(Cc2ccc(F)c(F)c2)c1=O)c1ccc(s1)-c1c[nH]c2ncccc12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University					Assay Description A PDK1 kinase assay was performed as follows. PDK1 (amino acids 51-360) and AKT2 (amino acids 140-467 fused to PIFtide, amino acids EEQEMFRDFDYIADW) ...				J Med Chem 51: 68-76 (2008) BindingDB Entry DOI: 10.7270/Q2H41TRT
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 [51-360] (Homo sapiens (Human))	BDBM366092 (US9873693, Compound 15 | US9873693, Compound 234) Show SMILES OC(=O)C[C@@H](NC(=O)c1cccn(Cc2ccc(F)c(F)c2)c1=O)c1ccc(s1)-c1c[nH]c2ncccc12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University					Assay Description A PDK1 kinase assay was performed as follows. PDK1 (amino acids 51-360) and AKT2 (amino acids 140-467 fused to PIFtide, amino acids EEQEMFRDFDYIADW) ...				J Med Chem 51: 68-76 (2008) BindingDB Entry DOI: 10.7270/Q2H41TRT
					More data for this Ligand-Target Pair