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BDBM3662 4-[(3-Bromophenyl)amino]-7-[[3-(4-morpholino)propyl]amino]pyrido[4,3-d]pyrimidine N1 -Oxide::4-[3-({4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin-7-yl}amino)propyl]-4-oxidomorpholin-4-ium::pyrido[4,3-d]pyrimidine deriv. 3t

SMILES: [O-][N+]1(CCCNc2cc3ncnc(Nc4cccc(Br)c4)c3cn2)CCOCC1

InChI Key: InChIKey=NMCVYFXROBUBLX-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3662   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3662
PNG
(4-[(3-Bromophenyl)amino]-7-[[3-(4-morpholino)propy...)
Show SMILES [O-][N+]1(CCCNc2cc3ncnc(Nc4cccc(Br)c4)c3cn2)CCOCC1
Show InChI InChI=1S/C20H23BrN6O2/c21-15-3-1-4-16(11-15)26-20-17-13-23-19(12-18(17)24-14-25-20)22-5-2-6-27(28)7-9-29-10-8-27/h1,3-4,11-14H,2,5-10H2,(H,22,23)(H,24,25,26)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.740n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 40: 3915-25 (1997)


Article DOI: 10.1021/jm970366v
BindingDB Entry DOI: 10.7270/Q2NS0S2V
More data for this
Ligand-Target Pair