BDBM36715 1-(2-benzoyl-4-chlorophenyl)-3-(3-chlorophenyl)thiourea

SMILES: Clc1cccc(NC(=S)Nc2ccc(Cl)cc2C(=O)c2ccccc2)c1

InChI Key: InChIKey=QNFMPFPZLAHXGG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 36715   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thymidylate synthase (Lactobacillus casei)	BDBM36715 (1-(2-benzoyl-4-chlorophenyl)-3-(3-chlorophenyl)thi...) Show SMILES Clc1cccc(NC(=S)Nc2ccc(Cl)cc2C(=O)c2ccccc2)c1 Show InChI InChI=1S/C20H14Cl2N2OS/c21-14-7-4-8-16(11-14)23-20(26)24-18-10-9-15(22)12-17(18)19(25)13-5-2-1-3-6-13/h1-12H,(H2,23,24,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	7.4	20
Northwestern University					Assay Description The enzyme assay were performed spectrophotometrically by following the absorbance at 340nm using a hewlett Packard 8453 UV spectrophotometer equippe...				Chem Biol 6: 319-31 (1999) Article DOI: 10.1016/S1074-5521(99)80077-5 BindingDB Entry DOI: 10.7270/Q2S180VB
					More data for this Ligand-Target Pair