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SMILES: COc1cc(OC)c2cc3c(nc(=S)[nH]c3=O)oc2c1

InChI Key: InChIKey=FZYGAYXYTXHBRG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 367250   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear factor NF-kappa-B p105 subunit (Homo sapiens (Human))	BDBM367250 (US10226464, Compound 18) Show SMILES COc1cc(OC)c2cc3c(nc(=S)[nH]c3=O)oc2c1 Show InChI InChI=1S/C13H10N2O4S/c1-17-6-3-9(18-2)7-5-8-11(16)14-13(20)15-12(8)19-10(7)4-6/h3-5H,1-2H3,(H,14,16,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description NFκB/Jurkat/GFP transcriptional reporter cell line was obtained from SBI System Biosciences. NF-κB/Jurkat/GFP™ Reporter cells (5×105 cells)...				Bioorg Med Chem Lett 17: 5384-9 (2007) BindingDB Entry DOI: 10.7270/Q2028TVG
					More data for this Ligand-Target Pair
Nuclear factor NF-kappa-B p105 subunit (Homo sapiens (Human))	BDBM367250 (US10226464, Compound 18) Show SMILES COc1cc(OC)c2cc3c(nc(=S)[nH]c3=O)oc2c1 Show InChI InChI=1S/C13H10N2O4S/c1-17-6-3-9(18-2)7-5-8-11(16)14-13(20)15-12(8)19-10(7)4-6/h3-5H,1-2H3,(H,14,16,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description DNA binding reaction (20 μL) was carried out in 1×DNA Binding Buffer (10 mM Tris, 40 mM NaCl, 1 mM EDTA, 4% glycerol) with 10 nM c-Rel protein a...				Bioorg Med Chem Lett 17: 5384-9 (2007) BindingDB Entry DOI: 10.7270/Q2028TVG
					More data for this Ligand-Target Pair