null

SMILES: CN1CCC(CC1)NC(=O)c1n[nH]c2ccc(cc12)-c1cccnc1

InChI Key: InChIKey=YEBVGOIYHPKGTI-HSZRJFAPSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 370062   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM370062 (US10669240, Compound 1) Show SMILES CN1CCC(CC1)NC(=O)c1n[nH]c2ccc(cc12)-c1cccnc1 Show InChI InChI=1S/C29H29F4N5O5/c1-15(2)23(35-24(39)19-13-17(29(31,32)33)5-7-20(19)30)25(40)37-11-9-28(10-12-37)26(41)36(4)27(42)38(28)18-6-8-22-21(14-18)34-16(3)43-22/h5-8,13-15,23H,9-12H2,1-4H3,(H,35,39)/t23-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	65	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description SH-SY5Y cells are cultured in DMEM/F-12 medium supplemented with 15% FBS, Non-essential Amino Acid and Penicillin/Streptamycin. Two days before treat...				US Patent US10669240 (2020) BindingDB Entry DOI: 10.7270/Q2HQ42ZD
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM370062 (US10669240, Compound 1) Show SMILES CN1CCC(CC1)NC(=O)c1n[nH]c2ccc(cc12)-c1cccnc1 Show InChI InChI=1S/C29H29F4N5O5/c1-15(2)23(35-24(39)19-13-17(29(31,32)33)5-7-20(19)30)25(40)37-11-9-28(10-12-37)26(41)36(4)27(42)38(28)18-6-8-22-21(14-18)34-16(3)43-22/h5-8,13-15,23H,9-12H2,1-4H3,(H,35,39)/t23-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description Reporter cell lines were generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a W...				US Patent US10669240 (2020) BindingDB Entry DOI: 10.7270/Q2HQ42ZD
					More data for this Ligand-Target Pair