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SMILES: Cn1ncc(N[C@H]2CCCN(Cc3ccccc3)C2)c(Cl)c1=O

InChI Key: InChIKey=XPMSGNKIIJCSLZ-AWEZNQCLSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 371528   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM371528
PNG
((S)-5-((1-benzylpiperidin-3-yl)amino)-4-chloro-2-m...)
Show SMILES Cn1ncc(N[C@H]2CCCN(Cc3ccccc3)C2)c(Cl)c1=O
Show InChI InChI=1S/C17H21ClN4O/c1-21-17(23)16(18)15(10-19-21)20-14-8-5-9-22(12-14)11-13-6-3-2-4-7-13/h2-4,6-7,10,14,20H,5,8-9,11-12H2,1H3/t14-/m0/s1
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 349n/an/an/an/an/an/a



GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair