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SMILES: Cn1ncc(NC2CCCN(CCCc3ccccc3)C2)c(Cl)c1=O

InChI Key: InChIKey=XADABVIZDHGDRT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 371561   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM371561
PNG
(Racemic-4-chloro-2-methyl-5-[[1-(3-phenylpropyl)-3...)
Show SMILES Cn1ncc(NC2CCCN(CCCc3ccccc3)C2)c(Cl)c1=O
Show InChI InChI=1S/C19H25ClN4O/c1-23-19(25)18(20)17(13-21-23)22-16-10-6-12-24(14-16)11-5-9-15-7-3-2-4-8-15/h2-4,7-8,13,16,22H,5-6,9-12,14H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
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PC cid
PC sid
UniChem
US Patent
n/an/a 232n/an/an/an/an/an/a



GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair