null

SMILES: OC(=O)c1ccc(cc1)-c1cc(ccc1[C@H]1CCOc2cc(ccc12)S(=O)(=O)Nc1cccc(F)n1)C(F)(F)F

InChI Key: InChIKey=FPZBPRHCYCZSPK-OAQYLSRUSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 371766   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM371766 (2'-(7-(N-(6-fluoropyridin-2-yl)sulfamoyl)chroman-4...) Show SMILES OC(=O)c1ccc(cc1)-c1cc(ccc1[C@H]1CCOc2cc(ccc12)S(=O)(=O)Nc1cccc(F)n1)C(F)(F)F |r| Show InChI InChI=1S/C28H20F4N2O5S/c29-25-2-1-3-26(33-25)34-40(37,38)19-9-11-22-21(12-13-39-24(22)15-19)20-10-8-18(28(30,31)32)14-23(20)16-4-6-17(7-5-16)27(35)36/h1-11,14-15,21H,12-13H2,(H,33,34)(H,35,36)/t21-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California at San Francisco					Assay Description HEK-293 cells overexpressing the channel of interest were seeded in a 96-well plate at a density of 30000 cells/well and incubated at 37° C./5% CO2 f...				J Med Chem 51: 545-52 (2008) BindingDB Entry DOI: 10.7270/Q2NG4SZX
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM371766 (2'-(7-(N-(6-fluoropyridin-2-yl)sulfamoyl)chroman-4...) Show SMILES OC(=O)c1ccc(cc1)-c1cc(ccc1[C@H]1CCOc2cc(ccc12)S(=O)(=O)Nc1cccc(F)n1)C(F)(F)F |r| Show InChI InChI=1S/C28H20F4N2O5S/c29-25-2-1-3-26(33-25)34-40(37,38)19-9-11-22-21(12-13-39-24(22)15-19)20-10-8-18(28(30,31)32)14-23(20)16-4-6-17(7-5-16)27(35)36/h1-11,14-15,21H,12-13H2,(H,33,34)(H,35,36)/t21-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
University of California at San Francisco					Assay Description HEK-293 cells overexpressing the channel of interest were seeded in a 96-well plate at a density of 30000 cells/well and incubated at 37° C./5% CO2 f...				J Med Chem 51: 545-52 (2008) BindingDB Entry DOI: 10.7270/Q2NG4SZX
					More data for this Ligand-Target Pair