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SMILES: N(c1ccccc1)c1ncc2[nH]c(cc2n1)-c1ccccc1

InChI Key: InChIKey=YHCGTIVCLOQBAU-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372148   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372148 (N,6-diphenyl-5H- pyrrolo[3,2- d]pyrimidin-2-amine ...) Show SMILES N(c1ccccc1)c1ncc2[nH]c(cc2n1)-c1ccccc1 Show InChI InChI=1S/C18H14N4/c1-3-7-13(8-4-1)15-11-16-17(21-15)12-19-18(22-16)20-14-9-5-2-6-10-14/h1-12,21H,(H,19,20,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
UNIVERSITY HEALTH NETWORK US Patent					Assay Description Active RIPK2 was purchased from Life Technologies as His-tagged of catalytic domain (amin acids 1-299) of human RIPK2 kinase expressed in insect cell...				US Patent US10875863 (2020)
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372148 (N,6-diphenyl-5H- pyrrolo[3,2- d]pyrimidin-2-amine ...) Show SMILES N(c1ccccc1)c1ncc2[nH]c(cc2n1)-c1ccccc1 Show InChI InChI=1S/C18H14N4/c1-3-7-13(8-4-1)15-11-16-17(21-15)12-19-18(22-16)20-14-9-5-2-6-10-14/h1-12,21H,(H,19,20,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair