null

SMILES: Cc1nc(Nc2ncc3[nH]c(cc3n2)-c2ccccc2C)cc(n1)N1CCN(CCO)CC1

InChI Key: InChIKey=UJEVYIZWXMCKQB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372152   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372152 (2-(4-(2-methyl- 6-((6- (o-tolyl)-5H- pyrrolo[3,2- ...) Show SMILES Cc1nc(Nc2ncc3[nH]c(cc3n2)-c2ccccc2C)cc(n1)N1CCN(CCO)CC1 Show InChI InChI=1S/C24H28N8O/c1-16-5-3-4-6-18(16)19-13-20-21(28-19)15-25-24(29-20)30-22-14-23(27-17(2)26-22)32-9-7-31(8-10-32)11-12-33/h3-6,13-15,28,33H,7-12H2,1-2H3,(H,25,26,27,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
UNIVERSITY HEALTH NETWORK US Patent					Assay Description Active RIPK2 was purchased from Life Technologies as His-tagged of catalytic domain (amin acids 1-299) of human RIPK2 kinase expressed in insect cell...				US Patent US10875863 (2020)
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372152 (2-(4-(2-methyl- 6-((6- (o-tolyl)-5H- pyrrolo[3,2- ...) Show SMILES Cc1nc(Nc2ncc3[nH]c(cc3n2)-c2ccccc2C)cc(n1)N1CCN(CCO)CC1 Show InChI InChI=1S/C24H28N8O/c1-16-5-3-4-6-18(16)19-13-20-21(28-19)15-25-24(29-20)30-22-14-23(27-17(2)26-22)32-9-7-31(8-10-32)11-12-33/h3-6,13-15,28,33H,7-12H2,1-2H3,(H,25,26,27,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair