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SMILES: C1CC(CCO1)c1cc2nc(Nc3cccc(c3)N3CCOCC3)ncc2[nH]1

InChI Key: InChIKey=KCJWOBHDPCYAJG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372161   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372161 (N-(3- morpholino- phenyl)-6- (tetrahydro-2H- pyran...) Show SMILES C1CC(CCO1)c1cc2nc(Nc3cccc(c3)N3CCOCC3)ncc2[nH]1 Show InChI InChI=1S/C21H25N5O2/c1-2-16(12-17(3-1)26-6-10-28-11-7-26)23-21-22-14-20-19(25-21)13-18(24-20)15-4-8-27-9-5-15/h1-3,12-15,24H,4-11H2,(H,22,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
UNIVERSITY HEALTH NETWORK US Patent					Assay Description Active RIPK2 was purchased from Life Technologies as His-tagged of catalytic domain (amin acids 1-299) of human RIPK2 kinase expressed in insect cell...				US Patent US10875863 (2020)
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372161 (N-(3- morpholino- phenyl)-6- (tetrahydro-2H- pyran...) Show SMILES C1CC(CCO1)c1cc2nc(Nc3cccc(c3)N3CCOCC3)ncc2[nH]1 Show InChI InChI=1S/C21H25N5O2/c1-2-16(12-17(3-1)26-6-10-28-11-7-26)23-21-22-14-20-19(25-21)13-18(24-20)15-4-8-27-9-5-15/h1-3,12-15,24H,4-11H2,(H,22,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair