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SMILES: Cc1ccccc1-c1cc2nc(NCC3(CCCC3)N3CCOCC3)ncc2[nH]1

InChI Key: InChIKey=UZVKIIMONNWMJQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372173   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372173 (N-((1- morpholino- cyclopentyl) methyl)-6- (o-toly...) Show SMILES Cc1ccccc1-c1cc2nc(NCC3(CCCC3)N3CCOCC3)ncc2[nH]1 Show InChI InChI=1S/C23H29N5O/c1-17-6-2-3-7-18(17)19-14-20-21(26-19)15-24-22(27-20)25-16-23(8-4-5-9-23)28-10-12-29-13-11-28/h2-3,6-7,14-15,26H,4-5,8-13,16H2,1H3,(H,24,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
UNIVERSITY HEALTH NETWORK US Patent					Assay Description Active RIPK2 was purchased from Life Technologies as His-tagged of catalytic domain (amin acids 1-299) of human RIPK2 kinase expressed in insect cell...				US Patent US10875863 (2020)
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM372173 (N-((1- morpholino- cyclopentyl) methyl)-6- (o-toly...) Show SMILES Cc1ccccc1-c1cc2nc(NCC3(CCCC3)N3CCOCC3)ncc2[nH]1 Show InChI InChI=1S/C23H29N5O/c1-17-6-2-3-7-18(17)19-14-20-21(26-19)15-24-22(27-20)25-16-23(8-4-5-9-23)28-10-12-29-13-11-28/h2-3,6-7,14-15,26H,4-5,8-13,16H2,1H3,(H,24,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...				J Med Chem 51: 2795-806 (2008) BindingDB Entry DOI: 10.7270/Q289186K
					More data for this Ligand-Target Pair