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SMILES: Fc1ccc(Cn2ncc(NC(=O)Cc3ccc(nc3)N3CCC(F)(F)C3)n2)cc1F

InChI Key: InChIKey=LHLJKMROMOKWOQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 372463   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))		BDBM372463
PNG
(N-[2-(3,4-Difluoro-benzyl)-2H-[1,2,3]triazol-4-yl]...)
Show SMILES Fc1ccc(Cn2ncc(NC(=O)Cc3ccc(nc3)N3CCC(F)(F)C3)n2)cc1F
Show InChI InChI=1S/C20H18F4N6O/c21-15-3-1-14(7-16(15)22)11-30-26-10-17(28-30)27-19(31)8-13-2-4-18(25-9-13)29-6-5-20(23,24)12-29/h1-4,7,9-10H,5-6,8,11-12H2,(H,27,28,31)
UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 7.30n/an/an/an/an/an/a



University of Alberta



Assay Description
Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...

J Med Chem 49: 1668-83 (2006)


BindingDB Entry DOI: 10.7270/Q2794709
More data for this
Ligand-Target Pair